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Data quality of whole genome bisulfite sequencing on Illumina platforms
The powerful HiSeq X sequencers with their patterned flowcell technology and fast turnaround times are instrumental for many large-scale genomic and epigenomic studies. However, assessment of DNA methylation by sodium bisulfite treatment results in sequencing libraries of low diversity, which may im...
Autores principales: | Raine, Amanda, Liljedahl, Ulrika, Nordlund, Jessica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905984/ https://www.ncbi.nlm.nih.gov/pubmed/29668744 http://dx.doi.org/10.1371/journal.pone.0195972 |
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