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Structural Determinants for the Interactions of Chemically Modified Nucleic Acids with the Stabilin-2 Clearance Receptor

[Image: see text] The Stabilin receptors are systemic clearance receptors for some classes of chemically modified nucleic acid therapeutics. In this study, the recombinant human secreted ecto-domain of the small isoform of Stabilin-2 (s190) was purified from cell culture and evaluated for direct bin...

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Detalles Bibliográficos
Autores principales:	Gaus, Hans, Miller, Colton M., Seth, Punit P., Harris, Edward N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2018
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905987/ https://www.ncbi.nlm.nih.gov/pubmed/29589907 http://dx.doi.org/10.1021/acs.biochem.8b00126

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