Case definitions for inclusion and analysis of endpoints in clinical trials for nonalcoholic steatohepatitis through the lens of regulatory science

Nonalcoholic steatohepatitis (NASH) is an important cause of liver‐related morbidity and mortality. There are no approved therapies, and the results of clinical trials have been difficult to compare due to inconsistent definitions of relevant disease parameters in patients with NASH. The natural cou...

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Detalles Bibliográficos
Autores principales: Siddiqui, Mohammad Shadab, Harrison, Stephen A., Abdelmalek, Manal F., Anstee, Quentin M., Bedossa, Pierre, Castera, Laurent, Dimick‐Santos, Lara, Friedman, Scott L., Greene, Katherine, Kleiner, David E., Megnien, Sophie, Neuschwander‐Tetri, Brent A., Ratziu, Vlad, Schabel, Elmer, Miller, Veronica, Sanyal, Arun J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Special Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906171/
https://www.ncbi.nlm.nih.gov/pubmed/29059456
http://dx.doi.org/10.1002/hep.29607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906171/
https://www.ncbi.nlm.nih.gov/pubmed/29059456
http://dx.doi.org/10.1002/hep.29607

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