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Improvement of cerebellar ataxic gait by injecting Cbln1 into the cerebellum of cbln1-null mice

Patients and rodents with cerebellar damage display ataxic gaits characterized by impaired coordination of limb movements. Here, gait ataxia in mice with a null mutation of the gene for the cerebellin 1 precursor protein (cbln1-null mice) was investigated by kinematic analysis of hindlimb movements...

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Detalles Bibliográficos
Autores principales: Takeuchi, Eri, Ito-Ishida, Aya, Yuzaki, Michisuke, Yanagihara, Dai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906462/
https://www.ncbi.nlm.nih.gov/pubmed/29670152
http://dx.doi.org/10.1038/s41598-018-24490-0