Novel naphthylpyridines from cobalt-catalyzed cyclotrimerization of a chiral diyne

ABSTRACT: The concise synthesis of a novel chiral diyne substrate for the assembly of chiral naphthylpyridines was described and different conditions for the cobalt-catalyzed co-cyclotrimerization with nitriles investigated. The products are novel naphthylpyridines possessing configurationally stabl...

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Detalles Bibliográficos
Autores principales: Trommer, Volkmar, Fischer, Fabian, Hapke, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2017
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906485/
https://www.ncbi.nlm.nih.gov/pubmed/29681656
http://dx.doi.org/10.1007/s00706-017-2083-9
Descripción
Sumario:ABSTRACT: The concise synthesis of a novel chiral diyne substrate for the assembly of chiral naphthylpyridines was described and different conditions for the cobalt-catalyzed co-cyclotrimerization with nitriles investigated. The products are novel naphthylpyridines possessing configurationally stable biaryl axes. GRAPHICAL ABSTRACT: [Image: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00706-017-2083-9) contains supplementary material, which is available to authorized users.

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