In situ analysis of FGFR2 mRNA and comparison with FGFR2 gene copy number by dual-color in situ hybridization in a large cohort of gastric cancer patients

BACKGROUND: Fibroblast growth factor receptor (FGFR2) has been proposed as a target in gastric cancer. However, appropriate methods to select patients for anti-FGFR2 therapies have not yet been established. METHODS: We used in situ techniques to investigate FGFR2 mRNA expression and gene amplificati...

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Detalles Bibliográficos
Autores principales: Kuboki, Yasutoshi, Schatz, Christoph A., Koechert, Karl, Schubert, Sabine, Feng, Janine, Wittemer-Rump, Sabine, Ziegelbauer, Karl, Krahn, Thomas, Nagatsuma, Akiko Kawano, Ochiai, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906494/
https://www.ncbi.nlm.nih.gov/pubmed/28852882
http://dx.doi.org/10.1007/s10120-017-0758-x

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