Cargando…

TERT promoter hotspot mutations in breast cancer

BACKGROUND: Telomerase reverse transcriptase (TERT) promoter mutations have been discovered in solid and hematological malignancies, where they reflect TERT activation and cell-cycle progression. In melanoma, glioma, and thyroid cancers, TERT promoter mutations are associated with a poor prognosis....

Descripción completa

Detalles Bibliográficos
Autores principales: Shimoi, Tatsunori, Yoshida, Masayuki, Kitamura, Yuka, Yoshino, Tomomi, Kawachi, Asuka, Shimomura, Akihiko, Noguchi, Emi, Yunokawa, Mayu, Yonemori, Kan, Shimizu, Chikako, Kinoshita, Takayuki, Ichimura, Koichi, Fukuda, Takahiro, Fujiwara, Yasuhiro, Tamura, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906518/
https://www.ncbi.nlm.nih.gov/pubmed/29222734
http://dx.doi.org/10.1007/s12282-017-0825-5

Ejemplares similares