DNA Damage Inducible Transcript 4 Gene: The Switch of the Metabolism as Potential Target in Cancer

DNA damage inducible transcript 4 (DDIT4) gene is expressed under stress situations turning off the metabolic activity triggered by the mammalian target of rapamycin (mTOR). Several in vitro and in vivo works have demonstrated the ability of DDIT4 to generate resistance to cancer therapy. The link b...

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Detalles Bibliográficos
Autores principales: Tirado-Hurtado, Indira, Fajardo, Williams, Pinto, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906527/
https://www.ncbi.nlm.nih.gov/pubmed/29707520
http://dx.doi.org/10.3389/fonc.2018.00106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906527/
https://www.ncbi.nlm.nih.gov/pubmed/29707520
http://dx.doi.org/10.3389/fonc.2018.00106

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