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Temporary sequestration of cholesterol and phosphatidylcholine within extracellular domains of ABCA1 during nascent HDL generation

The quality and quantity of high-density lipoprotein (HDL) in blood plasma are important for preventing coronary artery disease. ATP-binding cassette protein A1 (ABCA1) and apolipoprotein A-I (apoA-I) play essential roles in nascent HDL formation, but controversy persists regarding the mechanism by...

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Detalles Bibliográficos
Autores principales:	Ishigami, Masato, Ogasawara, Fumihiko, Nagao, Kohjiro, Hashimoto, Hidehiko, Kimura, Yasuhisa, Kioka, Noriyuki, Ueda, Kazumitsu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906560/ https://www.ncbi.nlm.nih.gov/pubmed/29670126 http://dx.doi.org/10.1038/s41598-018-24428-6

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