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Novel Polymyxin Combination With Antineoplastic Mitotane Improved the Bacterial Killing Against Polymyxin-Resistant Multidrug-Resistant Gram-Negative Pathogens

Due to limited new antibiotics, polymyxins are increasingly used to treat multidrug-resistant (MDR) Gram-negative bacteria, in particular carbapenem-resistant Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae. Unfortunately, polymyxin monotherapy has led to the emergence of...

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Detalles Bibliográficos
Autores principales:	Tran, Thien B., Wang, Jiping, Doi, Yohei, Velkov, Tony, Bergen, Phillip J., Li, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906568/ https://www.ncbi.nlm.nih.gov/pubmed/29706941 http://dx.doi.org/10.3389/fmicb.2018.00721

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