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Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin

The Chromobacterium sp. Panama bacterium has in vivo and in vitro anti-Plasmodium properties. To assess the nature of the Chromobacterium-produced anti-Plasmodium factors, chemical partition was conducted by bioassay-guided fractionation where different fractions were assayed for activity against as...

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Detalles Bibliográficos
Autores principales: Saraiva, Raúl G., Huitt-Roehl, Callie R., Tripathi, Abhai, Cheng, Yi-Qiang, Bosch, Jürgen, Townsend, Craig A., Dimopoulos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906607/
https://www.ncbi.nlm.nih.gov/pubmed/29670144
http://dx.doi.org/10.1038/s41598-018-24296-0