Cargando…

Tumor-associated macrophages promote progression and the Warburg effect via CCL18/NF-kB/VCAM-1 pathway in pancreatic ductal adenocarcinoma

Tumor-associated macrophages (TAMs) are frequently found near pancreatic cancer cells, but it is uncertain whether they are involved in pancreatic cancer progression and the Warburg effect. Here, we show that CCL18 secreted by TAMs facilitates malignant progression and induced a glycolytic phenotype...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ye, Huilin, Zhou, Quanbo, Zheng, Shangyou, Li, Guolin, Lin, Qing, Wei, Lusheng, Fu, Zhiqiang, Zhang, Bin, Liu, Yimin, Li, Zhihua, Chen, Rufu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906621/ https://www.ncbi.nlm.nih.gov/pubmed/29670110 http://dx.doi.org/10.1038/s41419-018-0486-0

Ejemplares similares

FEZF1-AS1/miR-107/ZNF312B axis facilitates progression and Warburg effect in pancreatic ductal adenocarcinoma
por: Ye, Huilin, et al.
Publicado: (2018)

circCUL2 induces an inflammatory CAF phenotype in pancreatic ductal adenocarcinoma via the activation of the MyD88-dependent NF-κB signaling pathway
por: Zheng, Shangyou, et al.
Publicado: (2022)

Cancer-associated fibroblasts promote progression and gemcitabine resistance via the SDF-1/SATB-1 pathway in pancreatic cancer
por: Wei, Lusheng, et al.
Publicado: (2018)

Correction: Cancer-associated fibroblasts promote progression and gemcitabine resistance via the SDF-1/SATB-1 pathway in pancreatic cancer
por: Wei, Lusheng, et al.
Publicado: (2021)

Endogenous miRNA Sponge LincRNA-ROR promotes proliferation, invasion and stem cell-like phenotype of pancreatic cancer cells
por: Fu, Zhiqiang, et al.
Publicado: (2017)

HIF‐2α regulates non‐canonical glutamine metabolism via activation of PI3K/mTORC2 pathway in human pancreatic ductal adenocarcinoma
por: Li, Wenzhu, et al.
Publicado: (2017)

High expression of AFAP1-AS1 is associated with poor survival and short-term recurrence in pancreatic ductal adenocarcinoma
por: Ye, Yibiao, et al.
Publicado: (2015)

Expression profile of long non-coding RNAs in pancreatic cancer and their clinical significance as biomarkers
por: Wang, Yingxue, et al.
Publicado: (2015)

Linc00511 acts as a competing endogenous RNA to regulate VEGFA expression through sponging hsa‐miR‐29b‐3p in pancreatic ductal adenocarcinoma
por: Zhao, Xiaohui, et al.
Publicado: (2017)

Cancer-associated fibroblasts-mediated ATF4 expression promotes malignancy and gemcitabine resistance in pancreatic cancer via the TGF-β1/SMAD2/3 pathway and ABCC1 transactivation
por: Wei, Lusheng, et al.
Publicado: (2021)

Circular RNA circBFAR promotes the progression of pancreatic ductal adenocarcinoma via the miR-34b-5p/MET/Akt axis
por: Guo, Xiaofeng, et al.
Publicado: (2020)

lncRNA-PLACT1 sustains activation of NF-κB pathway through a positive feedback loop with IκBα/E2F1 axis in pancreatic cancer
por: Ren, Xiaofan, et al.
Publicado: (2020)

Correction: lncRNA-PLACT1 sustains activation of NF-κB pathway through a positive feedback loop with IκBα/E2F1 axis in pancreatic cancer
por: Ren, Xiaofan, et al.
Publicado: (2022)

Cancer-associated fibroblast-induced lncRNA UPK1A-AS1 confers platinum resistance in pancreatic cancer via efficient double-strand break repair
por: Zhang, Xiang, et al.
Publicado: (2022)

LncRNA HOTAIR epigenetically suppresses miR-122 expression in hepatocellular carcinoma via DNA methylation
por: Cheng, Di, et al.
Publicado: (2018)

The long non-coding RNA HOTTIP promotes progression and gemcitabine resistance by regulating HOXA13 in pancreatic cancer
por: Li, Zhihua, et al.
Publicado: (2015)

A novel gene signature for prognosis prediction and chemotherapy response in patients with pancreatic cancer
por: Lin, Hongcao, et al.
Publicado: (2021)

Mutant KRAS Mediates circARFGEF2 Biogenesis to Promote Lymphatic Metastasis of Pancreatic Ductal Adenocarcinoma
por: Kong, Yao, et al.
Publicado: (2023)

circFARP1 enables cancer-associated fibroblasts to promote gemcitabine resistance in pancreatic cancer via the LIF/STAT3 axis
por: Hu, Chonghui, et al.
Publicado: (2022)

Involvement of the Akt/NF-κB Pathways in the HTNV-Mediated Increase of IL-6, CCL5, ICAM-1, and VCAM-1 in HUVECs
por: Yu, Haitao, et al.
Publicado: (2014)

Standard pancreatoduodenectomy versus extended pancreatoduodenectomy with modified retroperitoneal nerve resection in patients with pancreatic head cancer: a multicenter randomized controlled trial
por: Lin, Qing, et al.
Publicado: (2022)

Inhibition of glutamine metabolism counteracts pancreatic cancer stem cell features and sensitizes cells to radiotherapy
por: Li, Doudou, et al.
Publicado: (2015)

Single-cell RNA sequencing reveals spatiotemporal heterogeneity and malignant progression in pancreatic neuroendocrine tumor
por: Zhou, Yu, et al.
Publicado: (2021)

LLGL1 Regulates Gemcitabine Resistance by Modulating the ERK-SP1-OSMR Pathway in Pancreatic Ductal Adenocarcinoma
por: Zhu, Yin-Xin, et al.
Publicado: (2020)

NF-kB and the CLL microenvironment
por: O’Donnell, Alice, et al.
Publicado: (2023)

Nanocomplexation of thrombin with cationic amylose derivative for improved stability and hemostatic efficacy
por: Zhuang, Baoxiong, et al.
Publicado: (2015)

PCDH1 promotes progression of pancreatic ductal adenocarcinoma via activation of NF-κB signalling by interacting with KPNB1
por: Ye, Zhihua, et al.
Publicado: (2022)

CSTF2 mediated mRNA N(6)-methyladenosine modification drives pancreatic ductal adenocarcinoma m(6)A subtypes
por: Zheng, Yanfen, et al.
Publicado: (2023)

Macrophage migration inhibitory factor is overexpressed in pancreatic cancer tissues and impairs insulin secretion function of β-cell
por: Tan, Langping, et al.
Publicado: (2014)

Metabolic Phenotypes in Pancreatic Cancer
por: Yu, Min, et al.
Publicado: (2015)

Tumor-neuroglia interaction promotes pancreatic cancer metastasis
por: Su, Dan, et al.
Publicado: (2020)

Cancer-FOXP3 directly activated CCL5 to recruit FOXP3(+)Treg cells in pancreatic ductal adenocarcinoma
por: Wang, X, et al.
Publicado: (2017)

CCL2 produced by pancreatic ductal adenocarcinoma is essential for the accumulation and activation of monocytic myeloid‐derived suppressor cells
por: Gu, Haitao, et al.
Publicado: (2021)

Diisononyl phthalate aggravates allergic dermatitis by activation of NF-kB
por: Kang, Jun, et al.
Publicado: (2016)

NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma
por: Ramakrishnan, Gopalakrishnan, et al.
Publicado: (2022)

Characterization of NF-kB-mediated inhibition of catechol-O-methyltransferase
por: Tchivileva, Inna E, et al.
Publicado: (2009)

Chromatin accessibility uncovers KRAS-driven FOSL2 promoting pancreatic ductal adenocarcinoma progression through up-regulation of CCL28
por: Zhang, Shujun, et al.
Publicado: (2023)

NF-kB Expression in IgA Nephropathy Outcome
por: Silva, G. E. B., et al.
Publicado: (2011)

NF-kB pathway is involved in microscopic colitis pathogenesis
por: Pisani, Laura Francesca, et al.
Publicado: (2022)

Autophagy, Warburg, and Warburg Reverse Effects in Human Cancer
por: Gonzalez, Claudio D., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_l018spcsk466ug7snbmb55j1o8