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Inhibition of the mevalonate pathway enhances cancer cell oncolysis mediated by M1 virus
Oncolytic virus is an attractive anticancer agent that selectively lyses cancer through targeting cancer cells rather than normal cells. Although M1 virus is effective against several cancer types, certain cancer cells present low sensitivity to it. Here we identified that most of the components in...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906622/ https://www.ncbi.nlm.nih.gov/pubmed/29670091 http://dx.doi.org/10.1038/s41467-018-03913-6 |