Inhibition of the mevalonate pathway enhances cancer cell oncolysis mediated by M1 virus

Oncolytic virus is an attractive anticancer agent that selectively lyses cancer through targeting cancer cells rather than normal cells. Although M1 virus is effective against several cancer types, certain cancer cells present low sensitivity to it. Here we identified that most of the components in...

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Detalles Bibliográficos
Autores principales: Liang, Jiankai, Guo, Li, Li, Kai, Xiao, Xiao, Zhu, Wenbo, Zheng, Xiaoke, Hu, Jun, Zhang, Haipeng, Cai, Jing, Yu, Yaya, Tan, Yaqian, Li, Chuntao, Liu, Xincheng, Hu, Cheng, Liu, Ying, Qiu, Pengxin, Su, Xingwen, He, Songmin, Lin, Yuan, Yan, Guangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906622/
https://www.ncbi.nlm.nih.gov/pubmed/29670091
http://dx.doi.org/10.1038/s41467-018-03913-6

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