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Inhibition of cancer progression by a novel trans-stilbene derivative through disruption of microtubule dynamics, driving G2/M arrest, and p53-dependent apoptosis

Resveratrol, a trans-stilbene polyphenolic compound and its synthetic analogs are widely used bioactive molecules due to their remarkable chemo-preventive potential. Here, we have identified a novel synthetic trans-stilbene compound, Z-DAN-11 ((Z)-3-(3, 4-dimethoxyphenyl)-2-(3, 4, 5-trimethoxyphenyl...

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Detalles Bibliográficos
Autores principales: Parida, Pravat Kumar, Mahata, Barun, Santra, Abhisek, Chakraborty, Sohini, Ghosh, Zhumur, Raha, Sanghamitra, Misra, Anup Kumar, Biswas, Kaushik, Jana, Kuladip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906627/
https://www.ncbi.nlm.nih.gov/pubmed/29670107
http://dx.doi.org/10.1038/s41419-018-0476-2