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Perineuronal Net Protein Neurocan Inhibits NCAM/EphA3 Repellent Signaling in GABAergic Interneurons

Perineuronal nets (PNNs) are implicated in closure of critical periods of synaptic plasticity in the brain, but the molecular mechanisms by which PNNs regulate synapse development are obscure. A receptor complex of NCAM and EphA3 mediates postnatal remodeling of inhibitory perisomatic synapses of GA...

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Detalles Bibliográficos
Autores principales: Sullivan, Chelsea S., Gotthard, Ingo, Wyatt, Elliott V., Bongu, Srihita, Mohan, Vishwa, Weinberg, Richard J., Maness, Patricia F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906663/
https://www.ncbi.nlm.nih.gov/pubmed/29670169
http://dx.doi.org/10.1038/s41598-018-24272-8