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Perineuronal Net Protein Neurocan Inhibits NCAM/EphA3 Repellent Signaling in GABAergic Interneurons
Perineuronal nets (PNNs) are implicated in closure of critical periods of synaptic plasticity in the brain, but the molecular mechanisms by which PNNs regulate synapse development are obscure. A receptor complex of NCAM and EphA3 mediates postnatal remodeling of inhibitory perisomatic synapses of GA...
Autores principales: | Sullivan, Chelsea S., Gotthard, Ingo, Wyatt, Elliott V., Bongu, Srihita, Mohan, Vishwa, Weinberg, Richard J., Maness, Patricia F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906663/ https://www.ncbi.nlm.nih.gov/pubmed/29670169 http://dx.doi.org/10.1038/s41598-018-24272-8 |
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