Structural basis of epilepsy-related ligand–receptor complex LGI1–ADAM22

Epilepsy is a common brain disorder throughout history. Epilepsy-related ligand–receptor complex, LGI1–ADAM22, regulates synaptic transmission and has emerged as a determinant of brain excitability, as their mutations and acquired LGI1 autoantibodies cause epileptic disorders in human. Here, we repo...

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Detalles Bibliográficos
Autores principales: Yamagata, Atsushi, Miyazaki, Yuri, Yokoi, Norihiko, Shigematsu, Hideki, Sato, Yusuke, Goto-Ito, Sakurako, Maeda, Asami, Goto, Teppei, Sanbo, Makoto, Hirabayashi, Masumi, Shirouzu, Mikako, Fukata, Yuko, Fukata, Masaki, Fukai, Shuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906670/
https://www.ncbi.nlm.nih.gov/pubmed/29670100
http://dx.doi.org/10.1038/s41467-018-03947-w

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