Cargando…

Wogonin attenuates nasal polyp formation by inducing eosinophil apoptosis through HIF-1α and survivin suppression

Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) is an inflammatory sinonasal disorder characterized by eosinophilic inflammation and T-helper 2 skewing. Eosinophil accumulation in sinonasal mucosa comprises a major feature of CRSwNP. The study aimed to investigate the effect of the flavone w...

Descripción completa

Detalles Bibliográficos
Autores principales: Khalmuratova, Roza, Lee, Mingyu, Mo, Ji-Hun, Jung, YunJae, Park, Jong-Wan, Shin, Hyun-Woo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906673/
https://www.ncbi.nlm.nih.gov/pubmed/29670184
http://dx.doi.org/10.1038/s41598-018-24356-5