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Composite mathematical modeling of calcium signaling behind neuronal cell death in Alzheimer’s disease
BACKGROUND: Alzheimer’s disease (AD) is a progressive neurological disorder, recognized as the most common cause of dementia affecting people aged 65 and above. AD is characterized by an increase in amyloid metabolism, and by the misfolding and deposition of β-amyloid oligomers in and around neurons...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907315/ https://www.ncbi.nlm.nih.gov/pubmed/29671396 http://dx.doi.org/10.1186/s12918-018-0529-2 |