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Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods

The concept that abnormal protein aggregates show prion-like propagation between cells has been considered to explain the onset and progression of many neurodegenerative diseases. Indeed, both synthetic amyloid-like fibrils and pathogenic proteins extracted from patients’ brains induce self-template...

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Detalles Bibliográficos
Autores principales: Tarutani, Airi, Arai, Tetsuaki, Murayama, Shigeo, Hisanaga, Shin-ichi, Hasegawa, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907316/
https://www.ncbi.nlm.nih.gov/pubmed/29669601
http://dx.doi.org/10.1186/s40478-018-0532-2

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