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Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods
The concept that abnormal protein aggregates show prion-like propagation between cells has been considered to explain the onset and progression of many neurodegenerative diseases. Indeed, both synthetic amyloid-like fibrils and pathogenic proteins extracted from patients’ brains induce self-template...
Autores principales: | Tarutani, Airi, Arai, Tetsuaki, Murayama, Shigeo, Hisanaga, Shin-ichi, Hasegawa, Masato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907316/ https://www.ncbi.nlm.nih.gov/pubmed/29669601 http://dx.doi.org/10.1186/s40478-018-0532-2 |
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