miRNAs regulate immune response and signaling during hepatitis C virus infection

Hepatitis C is one of the most common types of viral hepatitis that impair human health. At present, there is still no effective specific therapy for hepatitis C virus infection. As host immunity is an important mechanism to defend against or clear infections, the interactions between the virus and...

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Detalles Bibliográficos
Autores principales: Zhu, Huange, Geng, Yan, He, Qian, Li, Miaoxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907448/
https://www.ncbi.nlm.nih.gov/pubmed/29669594
http://dx.doi.org/10.1186/s40001-018-0317-x
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author Zhu, Huange
Geng, Yan
He, Qian
Li, Miaoxian
author_facet Zhu, Huange
Geng, Yan
He, Qian
Li, Miaoxian
author_sort Zhu, Huange
collection PubMed
description Hepatitis C is one of the most common types of viral hepatitis that impair human health. At present, there is still no effective specific therapy for hepatitis C virus infection. As host immunity is an important mechanism to defend against or clear infections, the interactions between the virus and the host immune response are crucial to the progress of the disease. Of note, hepatitis C virus infection has been reported to regulate cellular miRNAs, which play significant roles in many processes, including infection and immunity. In this review, we describe how miRNAs regulate the host immune response to hepatitis C virus via complex signaling pathways.
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spelling pubmed-59074482018-04-30 miRNAs regulate immune response and signaling during hepatitis C virus infection Zhu, Huange Geng, Yan He, Qian Li, Miaoxian Eur J Med Res Review Hepatitis C is one of the most common types of viral hepatitis that impair human health. At present, there is still no effective specific therapy for hepatitis C virus infection. As host immunity is an important mechanism to defend against or clear infections, the interactions between the virus and the host immune response are crucial to the progress of the disease. Of note, hepatitis C virus infection has been reported to regulate cellular miRNAs, which play significant roles in many processes, including infection and immunity. In this review, we describe how miRNAs regulate the host immune response to hepatitis C virus via complex signaling pathways. BioMed Central 2018-04-18 /pmc/articles/PMC5907448/ /pubmed/29669594 http://dx.doi.org/10.1186/s40001-018-0317-x Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Zhu, Huange
Geng, Yan
He, Qian
Li, Miaoxian
miRNAs regulate immune response and signaling during hepatitis C virus infection
title miRNAs regulate immune response and signaling during hepatitis C virus infection
title_full miRNAs regulate immune response and signaling during hepatitis C virus infection
title_fullStr miRNAs regulate immune response and signaling during hepatitis C virus infection
title_full_unstemmed miRNAs regulate immune response and signaling during hepatitis C virus infection
title_short miRNAs regulate immune response and signaling during hepatitis C virus infection
title_sort mirnas regulate immune response and signaling during hepatitis c virus infection
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907448/
https://www.ncbi.nlm.nih.gov/pubmed/29669594
http://dx.doi.org/10.1186/s40001-018-0317-x
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AT limiaoxian mirnasregulateimmuneresponseandsignalingduringhepatitiscvirusinfection

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