Cargando…

Cognitive Function Before and After Left Heart Catheterization

BACKGROUND: Hospital procedures have been associated with cognitive change in older patients. This study aimed to document the prevalence of mild cognitive impairment in individuals undergoing left heart catheterization (LHC) before the procedure and the incidence of cognitive decline to 3 months af...

Descripción completa

Detalles Bibliográficos
Autores principales: Scott, David A., Evered, Lisbeth, Maruff, Paul, MacIsaac, Andrew, Maher, Sarah, Silbert, Brendan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907560/
https://www.ncbi.nlm.nih.gov/pubmed/29525780
http://dx.doi.org/10.1161/JAHA.117.008004
_version_ 1783315555099344896
author Scott, David A.
Evered, Lisbeth
Maruff, Paul
MacIsaac, Andrew
Maher, Sarah
Silbert, Brendan S.
author_facet Scott, David A.
Evered, Lisbeth
Maruff, Paul
MacIsaac, Andrew
Maher, Sarah
Silbert, Brendan S.
author_sort Scott, David A.
collection PubMed
description BACKGROUND: Hospital procedures have been associated with cognitive change in older patients. This study aimed to document the prevalence of mild cognitive impairment in individuals undergoing left heart catheterization (LHC) before the procedure and the incidence of cognitive decline to 3 months afterwards. METHODS AND RESULTS: We conducted a prospective, observational, clinical investigation of elderly participants undergoing elective LHC. Cognition was assessed using a battery of written tests and a computerized cognitive battery before the LHC and then at 3 months afterwards. The computerized tests were also administered at 24 hours (or discharge) and 7 days after LHC. A control group of 51 community participants was recruited to calculate cognitive decline using the Reliable Change Index. Of 437 participants, mild cognitive impairment was identified in 226 (51.7%) before the procedure. Computerized tests detected an incidence of cognitive decline of 10.0% at 24 hours and 7.5% at 7 days. At 3 months, written tests detected an incidence of cognitive decline of 13.1% and computerized tests detected an incidence of 8.5%. Cognitive decline at 3 months using written tests was associated with increasing age, whereas computerized tests showed cognitive decline was associated with baseline amnestic mild cognitive impairment, diabetes mellitus, and prior coronary stenting. CONCLUSIONS: More than half the patients aged >60 years presenting for LHC have mild cognitive impairment. LHC is followed by cognitive decline in 8% to 13% of individuals at 3 months after the procedure. Subtle cognitive decline both before and after LHC is common and may have important clinical implications. CLINICAL TRIAL REGISTRATION INFORMATION: URL: http://www.anzctr.org.au. Unique identifier: ACTRN12607000051448.
format Online
Article
Text
id pubmed-5907560
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-59075602018-05-01 Cognitive Function Before and After Left Heart Catheterization Scott, David A. Evered, Lisbeth Maruff, Paul MacIsaac, Andrew Maher, Sarah Silbert, Brendan S. J Am Heart Assoc Original Research BACKGROUND: Hospital procedures have been associated with cognitive change in older patients. This study aimed to document the prevalence of mild cognitive impairment in individuals undergoing left heart catheterization (LHC) before the procedure and the incidence of cognitive decline to 3 months afterwards. METHODS AND RESULTS: We conducted a prospective, observational, clinical investigation of elderly participants undergoing elective LHC. Cognition was assessed using a battery of written tests and a computerized cognitive battery before the LHC and then at 3 months afterwards. The computerized tests were also administered at 24 hours (or discharge) and 7 days after LHC. A control group of 51 community participants was recruited to calculate cognitive decline using the Reliable Change Index. Of 437 participants, mild cognitive impairment was identified in 226 (51.7%) before the procedure. Computerized tests detected an incidence of cognitive decline of 10.0% at 24 hours and 7.5% at 7 days. At 3 months, written tests detected an incidence of cognitive decline of 13.1% and computerized tests detected an incidence of 8.5%. Cognitive decline at 3 months using written tests was associated with increasing age, whereas computerized tests showed cognitive decline was associated with baseline amnestic mild cognitive impairment, diabetes mellitus, and prior coronary stenting. CONCLUSIONS: More than half the patients aged >60 years presenting for LHC have mild cognitive impairment. LHC is followed by cognitive decline in 8% to 13% of individuals at 3 months after the procedure. Subtle cognitive decline both before and after LHC is common and may have important clinical implications. CLINICAL TRIAL REGISTRATION INFORMATION: URL: http://www.anzctr.org.au. Unique identifier: ACTRN12607000051448. John Wiley and Sons Inc. 2018-03-10 /pmc/articles/PMC5907560/ /pubmed/29525780 http://dx.doi.org/10.1161/JAHA.117.008004 Text en © 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Research
Scott, David A.
Evered, Lisbeth
Maruff, Paul
MacIsaac, Andrew
Maher, Sarah
Silbert, Brendan S.
Cognitive Function Before and After Left Heart Catheterization
title Cognitive Function Before and After Left Heart Catheterization
title_full Cognitive Function Before and After Left Heart Catheterization
title_fullStr Cognitive Function Before and After Left Heart Catheterization
title_full_unstemmed Cognitive Function Before and After Left Heart Catheterization
title_short Cognitive Function Before and After Left Heart Catheterization
title_sort cognitive function before and after left heart catheterization
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907560/
https://www.ncbi.nlm.nih.gov/pubmed/29525780
http://dx.doi.org/10.1161/JAHA.117.008004
work_keys_str_mv AT scottdavida cognitivefunctionbeforeandafterleftheartcatheterization
AT everedlisbeth cognitivefunctionbeforeandafterleftheartcatheterization
AT maruffpaul cognitivefunctionbeforeandafterleftheartcatheterization
AT macisaacandrew cognitivefunctionbeforeandafterleftheartcatheterization
AT mahersarah cognitivefunctionbeforeandafterleftheartcatheterization
AT silbertbrendans cognitivefunctionbeforeandafterleftheartcatheterization