Cargando…

Modeling Short QT Syndrome Using Human‐Induced Pluripotent Stem Cell–Derived Cardiomyocytes

BACKGROUND: Short QT syndrome (SQTS), a disorder associated with characteristic ECG QT‐segment abbreviation, predisposes affected patients to sudden cardiac death. Despite some progress in assessing the organ‐level pathophysiology and genetic changes of the disorder, the understanding of the human c...

Descripción completa

Detalles Bibliográficos
Autores principales:	El‐Battrawy, Ibrahim, Lan, Huan, Cyganek, Lukas, Zhao, Zhihan, Li, Xin, Buljubasic, Fanis, Lang, Siegfried, Yücel, Gökhan, Sattler, Katherine, Zimmermann, Wolfram‐Hubertus, Utikal, Jochen, Wieland, Thomas, Ravens, Ursula, Borggrefe, Martin, Zhou, Xiao‐Bo, Akin, Ibrahim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907581/ https://www.ncbi.nlm.nih.gov/pubmed/29574456 http://dx.doi.org/10.1161/JAHA.117.007394

Ejemplares similares

Lipopolysaccharides induced inflammatory responses and electrophysiological dysfunctions in human-induced pluripotent stem cell derived cardiomyocytes
por: Yücel, Gökhan, et al.
Publicado: (2017)

Ion Channel Expression and Characterization in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Zhao, Zhihan, et al.
Publicado: (2018)

Serum of patients with acute myocardial infarction prevents inflammation in iPSC-cardiomyocytes
por: Sattler, Katherine, et al.
Publicado: (2019)

Hyperthermia Influences the Effects of Sodium Channel Blocking Drugs in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: El-Battrawy, Ibrahim, et al.
Publicado: (2016)

TRPV1 activation and internalization is part of the LPS-induced inflammation in human iPSC-derived cardiomyocytes
por: Sattler, Katherine, et al.
Publicado: (2021)

Nucleoside Diphosphate Kinase B Contributes to Arrhythmogenesis in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with Arrhythmogenic Right Ventricular Cardiomyopathy
por: Buljubasic, Fanis, et al.
Publicado: (2020)

Effects of Antiarrhythmic Drugs on hERG Gating in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1
por: Huang, Mengying, et al.
Publicado: (2021)

Studying Brugada Syndrome With an SCN1B Variants in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: El-Battrawy, Ibrahim, et al.
Publicado: (2019)

Ionic Mechanisms of Disopyramide Prolonging Action Potential Duration in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes From a Patient With Short QT Syndrome Type 1
por: Lan, Huan, et al.
Publicado: (2020)

Flagellin-Induced Immune Response in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Yuecel, Goekhan, et al.
Publicado: (2023)

Antiarrhythmic Effects of Vernakalant in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes from a Patient with Short QT Syndrome Type 1
por: Xu, Qiang, et al.
Publicado: (2022)

Regulation of Ion Channel Function in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes by Cancer Cell Secretion Through DNA Methylation
por: Zhong, Rujia, et al.
Publicado: (2022)

Impact of Antiarrhythmic Drugs on the Outcome of Short QT Syndrome
por: El-Battrawy, Ibrahim, et al.
Publicado: (2019)

Association of a congenital long QT syndrome type 1 with Takotsubo cardiomyopathy
por: El‐Battrawy, Ibrahim, et al.
Publicado: (2016)

Brugada Syndrome: Different Experimental Models and the Role of Human Cardiomyocytes From Induced Pluripotent Stem Cells
por: Li, Yingrui, et al.
Publicado: (2022)

Long‐Term Follow‐Up of Patients With Short QT Syndrome: Clinical Profile and Outcome
por: El‐Battrawy, Ibrahim, et al.
Publicado: (2018)

Sex-differences in short QT syndrome: A systematic literature review and pooled analysis
por: El-Battrawy, Ibrahim, et al.
Publicado: (2019)

Differences in Short QT Syndrome Subtypes: A Systematic Literature Review and Pooled Analysis
por: Raschwitz, Laura S., et al.
Publicado: (2020)

Glucose Counteracts Isoprenaline Effects on Ion Channel Functions in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Qiao, Lin, et al.
Publicado: (2022)

Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene‐edited human‐induced pluripotent stem cell‐derived cardiomyocytes and preclinical drug screening
por: El‐Battrawy, Ibrahim, et al.
Publicado: (2021)

Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Endothelial Cells
por: Fan, Xuehui, et al.
Publicado: (2022)

A Preclinical Study on Brugada Syndrome with a CACNB2 Variant Using Human Cardiomyocytes from Induced Pluripotent Stem Cells
por: Zhong, Rujia, et al.
Publicado: (2022)

Incidence and Prognostic Relevance of Cardiopulmonary Failure in Takotsubo Cardiomyopathy
por: El-Battrawy, Ibrahim, et al.
Publicado: (2017)

Lipopolysaccharide Modifies Sodium Current Kinetics through ROS and PKC Signalling in Induced Pluripotent Stem-Derived Cardiomyocytes from Brugada Syndrome Patient
por: Liao, Zhenxing, et al.
Publicado: (2022)

Dopamine D1/D5 Receptor Signaling Is Involved in Arrhythmogenesis in the Setting of Takotsubo Cardiomyopathy
por: Huang, Mengying, et al.
Publicado: (2022)

Corrigendum: Comparison and Outcome Analysis of Patients with Takotsubo Cardiomyopathy Triggered by Emotional Stress or Physical Stress
por: Giannakopoulos, Konstantinos, et al.
Publicado: (2017)

Comparison and Outcome Analysis of Patients with Takotsubo Cardiomyopathy Triggered by Emotional Stress or Physical Stress
por: Giannakopoulos, Konstantinos, et al.
Publicado: (2017)

Design and Rationale of the Femoral Closure versus Radial Compression Devices Related to Percutaneous Coronary Interventions (FERARI) Study
por: Behnes, Michael, et al.
Publicado: (2015)

Interventional Left Atrial Appendage Closure Affects the Metabolism of Acylcarnitines
por: Fastner, Christian, et al.
Publicado: (2018)

Age related differences and outcome of patients with Takotsubo syndrome
por: Huseynov, Aydin, et al.
Publicado: (2017)

Short‐term and long‐term incidence of stroke in Takotsubo syndrome
por: El‐Battrawy, Ibrahim, et al.
Publicado: (2018)

Short- and Long-Term Incidence of Thromboembolic Events in Takotsubo Syndrome as Compared With Acute Coronary Syndrome
por: El-Battrawy, Ibrahim, et al.
Publicado: (2019)

Implantable cardioverter‐defibrillator in Brugada syndrome: Long‐term follow‐up
por: El‐Battrawy, Ibrahim, et al.
Publicado: (2019)

Impact of ST-segment elevation on the outcome of Takotsubo syndrome
por: Gietzen, Thorsten, et al.
Publicado: (2019)

Clinical outcomes associated with catecholamine use in patients diagnosed with Takotsubo cardiomyopathy
por: Ansari, Uzair, et al.
Publicado: (2018)

Arrhythmic events in Brugada syndrome patients induced by fever
por: Roterberg, Gretje, et al.
Publicado: (2019)

The Use of Beta Blockers in Takotsubo Syndrome as Compared to Acute Coronary Syndrome
por: Kummer, Marvin, et al.
Publicado: (2020)

Impact of Sacubitril/Valsartan on the Long-Term Incidence of Ventricular Arrhythmias in Chronic Heart Failure Patients
por: El-Battrawy, Ibrahim, et al.
Publicado: (2019)

Novel insights in the pathomechanism of Brugada syndrome and fever‐related type 1 ECG changes in a preclinical study using human‐induced pluripotent stem cell‐derived cardiomyocytes
por: Li, Yingrui, et al.
Publicado: (2023)

Takotsubo syndrome and cardiac implantable electronic device therapy
por: El-Battrawy, Ibrahim, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_m508ab4paiqp08nvf5isd53g1l