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The Unexpected Role of Calcium‐Activated Potassium Channels: Limitation of NO‐Induced Arterial Relaxation

BACKGROUND: Multiple studies have shown that an NO‐induced activation of vascular smooth muscle BK channels contributes to the NO‐evoked dilation in many blood vessels. In vivo, NO is released continuously. NO attenuates vessel constrictions and, therefore, exerts an anticontractile effect. It is un...

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Detalles Bibliográficos
Autores principales: Schmid, Johannes, Müller, Bettina, Heppeler, David, Gaynullina, Dina, Kassmann, Mario, Gagov, Hristo, Mladenov, Mitko, Gollasch, Maik, Schubert, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907584/
https://www.ncbi.nlm.nih.gov/pubmed/29574460
http://dx.doi.org/10.1161/JAHA.117.007808