The Heteroaryldihydropyrimidine Bay 38-7690 Induces Hepatitis B Virus Core Protein Aggregates Associated with Promyelocytic Leukemia Nuclear Bodies in Infected Cells

Heteroaryldihydropyrimidines (HAPs) are compounds that inhibit hepatitis B virus (HBV) replication by modulating viral capsid assembly. While their biophysical effects on capsid assembly in vitro have been previously studied, the effect of HAP treatment on capsid protein (Cp) in individual HBV-infec...

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Detalles Bibliográficos
Autores principales: Huber, Andrew D., Wolf, Jennifer J., Liu, Dandan, Gres, Anna T., Tang, Jing, Boschert, Kelsey N., Puray-Chavez, Maritza N., Pineda, Dallas L., Laughlin, Thomas G., Coonrod, Emily M., Yang, Qiongying, Ji, Juan, Kirby, Karen A., Wang, Zhengqiang, Sarafianos, Stefan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907649/
https://www.ncbi.nlm.nih.gov/pubmed/29669885
http://dx.doi.org/10.1128/mSphereDirect.00131-18

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