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GALLIUM CITRATE, A NEW SENSITIZER OF CELLS TO HYPERTHERMIA

The killing effects of heat were studied on cultured mammalian cells (L5178Y) pre‐incubated with gallium (Ga) citrate, which is a popular tumor‐imaging diagnostic agent. The cells showed higher sensitivity to heat when they were pre‐incubated with Ga‐citrate. The pre‐incubated cells showed decreased...

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Detalles Bibliográficos
Autores principales: Shinohara, Kunio, Kawakami, Noriko, Kugotani, Maho, Nakano, Hisako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907758/
https://www.ncbi.nlm.nih.gov/pubmed/3128502
http://dx.doi.org/10.1111/j.1349-7006.1988.tb00006.x
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author Shinohara, Kunio
Kawakami, Noriko
Kugotani, Maho
Nakano, Hisako
author_facet Shinohara, Kunio
Kawakami, Noriko
Kugotani, Maho
Nakano, Hisako
author_sort Shinohara, Kunio
collection PubMed
description The killing effects of heat were studied on cultured mammalian cells (L5178Y) pre‐incubated with gallium (Ga) citrate, which is a popular tumor‐imaging diagnostic agent. The cells showed higher sensitivity to heat when they were pre‐incubated with Ga‐citrate. The pre‐incubated cells showed decreased ATP levels, and this may be responsible for the heat‐sensitizing effect.
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spelling pubmed-59077582018-05-11 GALLIUM CITRATE, A NEW SENSITIZER OF CELLS TO HYPERTHERMIA Shinohara, Kunio Kawakami, Noriko Kugotani, Maho Nakano, Hisako Jpn J Cancer Res Rapid Communication The killing effects of heat were studied on cultured mammalian cells (L5178Y) pre‐incubated with gallium (Ga) citrate, which is a popular tumor‐imaging diagnostic agent. The cells showed higher sensitivity to heat when they were pre‐incubated with Ga‐citrate. The pre‐incubated cells showed decreased ATP levels, and this may be responsible for the heat‐sensitizing effect. Blackwell Publishing Ltd 1988-01 /pmc/articles/PMC5907758/ /pubmed/3128502 http://dx.doi.org/10.1111/j.1349-7006.1988.tb00006.x Text en
spellingShingle Rapid Communication
Shinohara, Kunio
Kawakami, Noriko
Kugotani, Maho
Nakano, Hisako
GALLIUM CITRATE, A NEW SENSITIZER OF CELLS TO HYPERTHERMIA
title GALLIUM CITRATE, A NEW SENSITIZER OF CELLS TO HYPERTHERMIA
title_full GALLIUM CITRATE, A NEW SENSITIZER OF CELLS TO HYPERTHERMIA
title_fullStr GALLIUM CITRATE, A NEW SENSITIZER OF CELLS TO HYPERTHERMIA
title_full_unstemmed GALLIUM CITRATE, A NEW SENSITIZER OF CELLS TO HYPERTHERMIA
title_short GALLIUM CITRATE, A NEW SENSITIZER OF CELLS TO HYPERTHERMIA
title_sort gallium citrate, a new sensitizer of cells to hyperthermia
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907758/
https://www.ncbi.nlm.nih.gov/pubmed/3128502
http://dx.doi.org/10.1111/j.1349-7006.1988.tb00006.x
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