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A B‐CELL LINE HAVING CHROMOSOME 14 ABERRATION AT BREAK BAND qll DERIVED FROM AN ADULT T‐CELL LEUKEMIA PATIENT

A B‐cell line having translocations of chromosome 14 at break band q11 (the assigned locus of the α‐chain gene of the T‐cell antigen receptor) and chromosome 3 at break band p25 (the assigned locus of the c‐raf‐1 oncogene) was established from peripheral blood leukocytes of an adult T‐cell leukemia...

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Autores principales: Miyamoto, Kanji, Matsuoka, Masao, Tomita, Noriko, Suzuki, Chieko, Sato, Yasushi, Ishii, Akio, Kitajima, Ko‐ichi, Nonaka, Hiroshi, Kondo, Toshifumi, Hiraki, Yoshio, Kobayashi, Nobuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907761/
https://www.ncbi.nlm.nih.gov/pubmed/2895757
http://dx.doi.org/10.1111/j.1349-7006.1988.tb00004.x
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author Miyamoto, Kanji
Matsuoka, Masao
Tomita, Noriko
Suzuki, Chieko
Sato, Yasushi
Ishii, Akio
Kitajima, Ko‐ichi
Nonaka, Hiroshi
Kondo, Toshifumi
Hiraki, Yoshio
Kobayashi, Nobuyuki
author_facet Miyamoto, Kanji
Matsuoka, Masao
Tomita, Noriko
Suzuki, Chieko
Sato, Yasushi
Ishii, Akio
Kitajima, Ko‐ichi
Nonaka, Hiroshi
Kondo, Toshifumi
Hiraki, Yoshio
Kobayashi, Nobuyuki
author_sort Miyamoto, Kanji
collection PubMed
description A B‐cell line having translocations of chromosome 14 at break band q11 (the assigned locus of the α‐chain gene of the T‐cell antigen receptor) and chromosome 3 at break band p25 (the assigned locus of the c‐raf‐1 oncogene) was established from peripheral blood leukocytes of an adult T‐cell leukemia (ATL) patient. The same chromosome 14 aberration at break band q11 and chromosome 3 aberration at break band p25 were also found in fresh T‐cell leukemia cells. The B‐cell line is surface immunoglobulin (sIg)(+), immunoglobulin gene rearrangement(+), ATL‐specific antigen (ATLA)(+), HTLV‐1 proviral genome(+), Epstein‐Barr virus (EBV)‐associated nuclear antigen (EBNA)(+) and the EBV DNA genome(+). The fresh T‐leukemic cells were T‐cell receptor gene rearrangement(+), the HTLV‐1 proviral genome(+) and EBV DNA genome(−).
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spelling pubmed-59077612018-05-11 A B‐CELL LINE HAVING CHROMOSOME 14 ABERRATION AT BREAK BAND qll DERIVED FROM AN ADULT T‐CELL LEUKEMIA PATIENT Miyamoto, Kanji Matsuoka, Masao Tomita, Noriko Suzuki, Chieko Sato, Yasushi Ishii, Akio Kitajima, Ko‐ichi Nonaka, Hiroshi Kondo, Toshifumi Hiraki, Yoshio Kobayashi, Nobuyuki Jpn J Cancer Res Rapid Communication A B‐cell line having translocations of chromosome 14 at break band q11 (the assigned locus of the α‐chain gene of the T‐cell antigen receptor) and chromosome 3 at break band p25 (the assigned locus of the c‐raf‐1 oncogene) was established from peripheral blood leukocytes of an adult T‐cell leukemia (ATL) patient. The same chromosome 14 aberration at break band q11 and chromosome 3 aberration at break band p25 were also found in fresh T‐cell leukemia cells. The B‐cell line is surface immunoglobulin (sIg)(+), immunoglobulin gene rearrangement(+), ATL‐specific antigen (ATLA)(+), HTLV‐1 proviral genome(+), Epstein‐Barr virus (EBV)‐associated nuclear antigen (EBNA)(+) and the EBV DNA genome(+). The fresh T‐leukemic cells were T‐cell receptor gene rearrangement(+), the HTLV‐1 proviral genome(+) and EBV DNA genome(−). Blackwell Publishing Ltd 1988-01 /pmc/articles/PMC5907761/ /pubmed/2895757 http://dx.doi.org/10.1111/j.1349-7006.1988.tb00004.x Text en
spellingShingle Rapid Communication
Miyamoto, Kanji
Matsuoka, Masao
Tomita, Noriko
Suzuki, Chieko
Sato, Yasushi
Ishii, Akio
Kitajima, Ko‐ichi
Nonaka, Hiroshi
Kondo, Toshifumi
Hiraki, Yoshio
Kobayashi, Nobuyuki
A B‐CELL LINE HAVING CHROMOSOME 14 ABERRATION AT BREAK BAND qll DERIVED FROM AN ADULT T‐CELL LEUKEMIA PATIENT
title A B‐CELL LINE HAVING CHROMOSOME 14 ABERRATION AT BREAK BAND qll DERIVED FROM AN ADULT T‐CELL LEUKEMIA PATIENT
title_full A B‐CELL LINE HAVING CHROMOSOME 14 ABERRATION AT BREAK BAND qll DERIVED FROM AN ADULT T‐CELL LEUKEMIA PATIENT
title_fullStr A B‐CELL LINE HAVING CHROMOSOME 14 ABERRATION AT BREAK BAND qll DERIVED FROM AN ADULT T‐CELL LEUKEMIA PATIENT
title_full_unstemmed A B‐CELL LINE HAVING CHROMOSOME 14 ABERRATION AT BREAK BAND qll DERIVED FROM AN ADULT T‐CELL LEUKEMIA PATIENT
title_short A B‐CELL LINE HAVING CHROMOSOME 14 ABERRATION AT BREAK BAND qll DERIVED FROM AN ADULT T‐CELL LEUKEMIA PATIENT
title_sort b‐cell line having chromosome 14 aberration at break band qll derived from an adult t‐cell leukemia patient
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907761/
https://www.ncbi.nlm.nih.gov/pubmed/2895757
http://dx.doi.org/10.1111/j.1349-7006.1988.tb00004.x
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