Reduction of Circulating Cancer Cells and Metastases in Breast-Cancer Models by a Potent EphA2-Agonistic Peptide–Drug Conjugate

[Image: see text] EphA2 overexpression has been associated with metastasis in multiple cancer types, including melanomas and ovarian, prostate, lung, and breast cancers. We have recently proposed the development of peptide–drug conjugates (PDCs) using agonistic EphA2-targeting agents, such as the YS...

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Detalles Bibliográficos
Autores principales: Salem, Ahmed F., Wang, Si, Billet, Sandrine, Chen, Jie-Fu, Udompholkul, Parima, Gambini, Luca, Baggio, Carlo, Tseng, Hsian-Rong, Posadas, Edwin M., Bhowmick, Neil A., Pellecchia, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907794/
https://www.ncbi.nlm.nih.gov/pubmed/29470068
http://dx.doi.org/10.1021/acs.jmedchem.7b01837

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