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Efficient gene transfection to the brain with ultrasound irradiation in mice using stabilized bubble lipopolyplexes prepared by the surface charge regulation method
INTRODUCTION: We previously developed anionic ternary bubble lipopolyplexes, an ultrasound-responsive carrier, expecting safe and efficient gene transfection. However, bubble lipopolyplexes have a low capacity for echo gas (C(3)F(8)) encapsulation (EGE) in nonionic solution such as 5% glucose. On th...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907898/ https://www.ncbi.nlm.nih.gov/pubmed/29713163 http://dx.doi.org/10.2147/IJN.S157375 |