Changes in N-glycans of IgG4 and its relationship with the existence of hypocomplementemia and individual organ involvement in patients with IgG4-related disease

BACKGROUND: Although increased serum IgG4 level and tissue infiltration of IgG4-positive cells are key events in IgG4-related disease (IgG4RD), and nearly half of IgG4RD patients show hypocomplementemia, the role of IgG4 in the pathogenesis of IgG4RD remains unclear. Many reports show that altered I...

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Detalles Bibliográficos
Autores principales: Konno, Naoki, Sugimoto, Mitsuru, Takagi, Tadayuki, Furuya, Makiko, Asano, Tomoyuki, Sato, Shuzo, Kobayashi, Hiroko, Migita, Kiyoshi, Miura, Yoshiaki, Aihara, Taichi, Komatsuda, Atsushi, Ohira, Hiromasa, Watanabe, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908088/
https://www.ncbi.nlm.nih.gov/pubmed/29672582
http://dx.doi.org/10.1371/journal.pone.0196163

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