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Unique mechanisms of connective tissue growth factor regulation in airway smooth muscle in asthma: Relationship with airway remodelling

Neovascularization, increased basal membrane thickness and increased airway smooth muscle (ASM) bulk are hallmarks of airway remodelling in asthma. In this study, we examined connective tissue growth factor (CTGF) dysregulation in human lung tissue and animal models of allergic airway disease. Immun...

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Detalles Bibliográficos
Autores principales: Wang, Junfei, Faiz, Alen, Ge, Qi, Vermeulen, Cornelis J., Van der Velden, Joanne, Snibson, Kenneth J., van de Velde, Rob, Sawant, Sonia, Xenaki, Dikaia, Oliver, Brian, Timens, Wim, ten Hacken, Nick, van den Berge, Maarten, James, Alan, Elliot, John G., Dong, Liang, Burgess, Janette K., Ashton, Anthony W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908101/
https://www.ncbi.nlm.nih.gov/pubmed/29516637
http://dx.doi.org/10.1111/jcmm.13576

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