Cargando…
FGF1 improves functional recovery through inducing PRDX1 to regulate autophagy and anti‐ROS after spinal cord injury
Fibroblast growth factor 1 (FGF1) is thought to exert protective and regenerative effects on neurons following spinal cord injury (SCI), although the mechanism of these effects is not well understood. The use of FGF1 as a therapeutic agent is limited by its lack of physicochemical stability and its...
Autores principales: | Li, Jiawei, Wang, Qingqing, Cai, Hanxiao, He, Zili, Wang, Haoli, Chen, Jian, Zheng, Zengming, Yin, Jiayu, Liao, Zhiyong, Xu, Huazi, Xiao, Jian, Gong, Fanghua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908106/ https://www.ncbi.nlm.nih.gov/pubmed/29512938 http://dx.doi.org/10.1111/jcmm.13566 |
Ejemplares similares
-
Liraglutide activates autophagy via GLP-1R to improve functional recovery after spinal cord injury
por: Chen, Jian, et al.
Publicado: (2017) -
The cross-talk between autophagy and endoplasmic reticulum stress in blood-spinal cord barrier disruption after spinal cord injury
por: Zhou, Yulong, et al.
Publicado: (2016) -
Hydrogen Sulfide Ameliorates Blood-Spinal Cord Barrier Disruption and Improves Functional Recovery by Inhibiting Endoplasmic Reticulum Stress-Dependent Autophagy
por: Wang, Haoli, et al.
Publicado: (2018) -
Neuron and microglia/macrophage-derived FGF10 activate neuronal FGFR2/PI3K/Akt signaling and inhibit microglia/macrophages TLR4/NF-κB-dependent neuroinflammation to improve functional recovery after spinal cord injury
por: Chen, Jian, et al.
Publicado: (2017) -
Spermidine promotes nucleus pulposus autophagy as a protective mechanism against apoptosis and ameliorates disc degeneration
por: Zheng, Zengming, et al.
Publicado: (2018)