NF‐κB inhibition reverses acidic bile‐induced miR‐21, miR‐155, miR‐192, miR‐34a, miR‐375 and miR‐451a deregulations in human hypopharyngeal cells

We previously demonstrated that acidic bile activates NF‐κB, deregulating the expression of oncogenic miRNA markers, in pre‐malignant murine laryngopharyngeal mucosa. Here, we hypothesize that the in vitro exposure of human hypopharyngeal cells to acidic bile deregulates cancer‐related miRNA markers...

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Detalles Bibliográficos
Autores principales: Doukas, Sotirios G., Vageli, Dimitra P., Sasaki, Clarence T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908126/
https://www.ncbi.nlm.nih.gov/pubmed/29516639
http://dx.doi.org/10.1111/jcmm.13591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908126/
https://www.ncbi.nlm.nih.gov/pubmed/29516639
http://dx.doi.org/10.1111/jcmm.13591

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