Cargando…
Value of perioperative genitourinary screening culture and colonization status in predicting early urinary tract infection after renal transplantation
BACKGROUND: We aimed to assess whether patients colonized with certain organisms in the genitourinary tract would have greater urinary tract infection (UTI) risk during the post-transplantation period, and whether information on the perioperatively colonized organisms may help identify the causal or...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908147/ https://www.ncbi.nlm.nih.gov/pubmed/29672580 http://dx.doi.org/10.1371/journal.pone.0196115 |
_version_ | 1783315668277395456 |
---|---|
author | Han, Ahram Ahn, Sanghyun Min, Seung-Kee Ha, Jongwon Kim, Yon Su Ahn, Curie Min, Sang-il |
author_facet | Han, Ahram Ahn, Sanghyun Min, Seung-Kee Ha, Jongwon Kim, Yon Su Ahn, Curie Min, Sang-il |
author_sort | Han, Ahram |
collection | PubMed |
description | BACKGROUND: We aimed to assess whether patients colonized with certain organisms in the genitourinary tract would have greater urinary tract infection (UTI) risk during the post-transplantation period, and whether information on the perioperatively colonized organisms may help identify the causal organisms during early UTI. METHODS: We retrospectively reviewed the culture results of preoperative urine, preoperative urethral swab, and postoperative urinary catheter tip specimens of 420 renal transplant recipients. The colonization status was compared to the culture results during the first UTI episode within 6 months after transplantation. RESULTS: Twenty six (6.2%) patients developed early UTI, and the presence of common uropathogens in the perioperative genitourinary specimen was positively associated with a higher early UTI risk odds ratio [OR], 3.23; 95% confidence interval [CI], 1.44 to 7.24; P = 0.003). However, the actual causal organism during UTI was observed perioperatively only in 15 patients (40.5%). Neither perioperative colonization nor early UTI was associated with subsequent acute cellular rejection or graft failure. CONCLUSIONS: Renal transplantation patients who were colonized with common uropathogens were more likely to develop early UTI. However, the usefulness of the culture results of perioperative colonizers in predicting the causal organism during early UTI seems limited due to the low concordance rate. |
format | Online Article Text |
id | pubmed-5908147 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-59081472018-05-04 Value of perioperative genitourinary screening culture and colonization status in predicting early urinary tract infection after renal transplantation Han, Ahram Ahn, Sanghyun Min, Seung-Kee Ha, Jongwon Kim, Yon Su Ahn, Curie Min, Sang-il PLoS One Research Article BACKGROUND: We aimed to assess whether patients colonized with certain organisms in the genitourinary tract would have greater urinary tract infection (UTI) risk during the post-transplantation period, and whether information on the perioperatively colonized organisms may help identify the causal organisms during early UTI. METHODS: We retrospectively reviewed the culture results of preoperative urine, preoperative urethral swab, and postoperative urinary catheter tip specimens of 420 renal transplant recipients. The colonization status was compared to the culture results during the first UTI episode within 6 months after transplantation. RESULTS: Twenty six (6.2%) patients developed early UTI, and the presence of common uropathogens in the perioperative genitourinary specimen was positively associated with a higher early UTI risk odds ratio [OR], 3.23; 95% confidence interval [CI], 1.44 to 7.24; P = 0.003). However, the actual causal organism during UTI was observed perioperatively only in 15 patients (40.5%). Neither perioperative colonization nor early UTI was associated with subsequent acute cellular rejection or graft failure. CONCLUSIONS: Renal transplantation patients who were colonized with common uropathogens were more likely to develop early UTI. However, the usefulness of the culture results of perioperative colonizers in predicting the causal organism during early UTI seems limited due to the low concordance rate. Public Library of Science 2018-04-19 /pmc/articles/PMC5908147/ /pubmed/29672580 http://dx.doi.org/10.1371/journal.pone.0196115 Text en © 2018 Han et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Han, Ahram Ahn, Sanghyun Min, Seung-Kee Ha, Jongwon Kim, Yon Su Ahn, Curie Min, Sang-il Value of perioperative genitourinary screening culture and colonization status in predicting early urinary tract infection after renal transplantation |
title | Value of perioperative genitourinary screening culture and colonization status in predicting early urinary tract infection after renal transplantation |
title_full | Value of perioperative genitourinary screening culture and colonization status in predicting early urinary tract infection after renal transplantation |
title_fullStr | Value of perioperative genitourinary screening culture and colonization status in predicting early urinary tract infection after renal transplantation |
title_full_unstemmed | Value of perioperative genitourinary screening culture and colonization status in predicting early urinary tract infection after renal transplantation |
title_short | Value of perioperative genitourinary screening culture and colonization status in predicting early urinary tract infection after renal transplantation |
title_sort | value of perioperative genitourinary screening culture and colonization status in predicting early urinary tract infection after renal transplantation |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908147/ https://www.ncbi.nlm.nih.gov/pubmed/29672580 http://dx.doi.org/10.1371/journal.pone.0196115 |
work_keys_str_mv | AT hanahram valueofperioperativegenitourinaryscreeningcultureandcolonizationstatusinpredictingearlyurinarytractinfectionafterrenaltransplantation AT ahnsanghyun valueofperioperativegenitourinaryscreeningcultureandcolonizationstatusinpredictingearlyurinarytractinfectionafterrenaltransplantation AT minseungkee valueofperioperativegenitourinaryscreeningcultureandcolonizationstatusinpredictingearlyurinarytractinfectionafterrenaltransplantation AT hajongwon valueofperioperativegenitourinaryscreeningcultureandcolonizationstatusinpredictingearlyurinarytractinfectionafterrenaltransplantation AT kimyonsu valueofperioperativegenitourinaryscreeningcultureandcolonizationstatusinpredictingearlyurinarytractinfectionafterrenaltransplantation AT ahncurie valueofperioperativegenitourinaryscreeningcultureandcolonizationstatusinpredictingearlyurinarytractinfectionafterrenaltransplantation AT minsangil valueofperioperativegenitourinaryscreeningcultureandcolonizationstatusinpredictingearlyurinarytractinfectionafterrenaltransplantation |