Cargando…

Intravascular ultrasound assisted sizing in thoracic endovascular aortic repair improves aortic remodeling in Type B aortic dissection

The precise sizing of the stent graft in thoracic endovascular aortic repair (TEVAR) affects aortic remodeling and hence, further outcome. Covering the proximal entry tear is essential for successful treatment of Type B aortic dissection. Intravascular ultrasound (IVUS) enables real-time aortic diam...

Descripción completa

Detalles Bibliográficos
Autores principales: Lortz, Julia, Tsagakis, Konstantinos, Rammos, Christos, Horacek, Michael, Schlosser, Thomas, Jakob, Heinz, Rassaf, Tienush, Jánosi, Rolf Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908162/
https://www.ncbi.nlm.nih.gov/pubmed/29672613
http://dx.doi.org/10.1371/journal.pone.0196180
_version_ 1783315671759716352
author Lortz, Julia
Tsagakis, Konstantinos
Rammos, Christos
Horacek, Michael
Schlosser, Thomas
Jakob, Heinz
Rassaf, Tienush
Jánosi, Rolf Alexander
author_facet Lortz, Julia
Tsagakis, Konstantinos
Rammos, Christos
Horacek, Michael
Schlosser, Thomas
Jakob, Heinz
Rassaf, Tienush
Jánosi, Rolf Alexander
author_sort Lortz, Julia
collection PubMed
description The precise sizing of the stent graft in thoracic endovascular aortic repair (TEVAR) affects aortic remodeling and hence, further outcome. Covering the proximal entry tear is essential for successful treatment of Type B aortic dissection. Intravascular ultrasound (IVUS) enables real-time aortic diameter assessment, and is especially useful when computed tomography (CT) image quality is poor. IVUS, however, is not routinely utilized due to cost inefficiency. We investigated the impact of IVUS-assisted stent graft sizing on aortic remodeling in TEVAR. In this single-center retrospective study we evaluated patients with Type B aortic dissection undergoing both CT and IVUS before TEVAR. We assessed the aortic diameter at the level of the left subclavian artery via both methods before stent implantation and analyzed due to which method the implanted stent graft was chosen, retrospectively. To determine the degrees of aortic remodeling involved, we evaluated true lumen and false lumen diameters, and total aortic remodeling in CT. We analyzed 45 patients with Type B aortic dissection undergoing TEVAR. The mean ages were 66.9±10.0 years fo0072 IVUS (n = 20) and 62.3±14.2 years for CT-assisted TEVAR (n = 25; p = 0.226). The follow-up time for both groups did not differ between the two groups (IVUS: 22.9±23.1 months, CT: 25.6±23.0 months; p = 0.700). While both methods were associated with advantages regarding aortic remodeling, IVUS-assisted sizing yielded a greater increase in true lumen (30.4±6.2 vs. 25.6±5.3; p = 0.008) and reductions in false lumen (14.4±8.5 vs. 23.9±9.3; p = 0.001) and total aortic diameter (35.5±6.0 vs. 39.9±8.1; p = 0.045). IVUS-guided stent graft sizing in Type B aortic dissection shows beneficial effects on aortic remodeling and might be of additional advantage in aortic diseases, especially when CT image quality is poor.
format Online
Article
Text
id pubmed-5908162
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-59081622018-05-06 Intravascular ultrasound assisted sizing in thoracic endovascular aortic repair improves aortic remodeling in Type B aortic dissection Lortz, Julia Tsagakis, Konstantinos Rammos, Christos Horacek, Michael Schlosser, Thomas Jakob, Heinz Rassaf, Tienush Jánosi, Rolf Alexander PLoS One Research Article The precise sizing of the stent graft in thoracic endovascular aortic repair (TEVAR) affects aortic remodeling and hence, further outcome. Covering the proximal entry tear is essential for successful treatment of Type B aortic dissection. Intravascular ultrasound (IVUS) enables real-time aortic diameter assessment, and is especially useful when computed tomography (CT) image quality is poor. IVUS, however, is not routinely utilized due to cost inefficiency. We investigated the impact of IVUS-assisted stent graft sizing on aortic remodeling in TEVAR. In this single-center retrospective study we evaluated patients with Type B aortic dissection undergoing both CT and IVUS before TEVAR. We assessed the aortic diameter at the level of the left subclavian artery via both methods before stent implantation and analyzed due to which method the implanted stent graft was chosen, retrospectively. To determine the degrees of aortic remodeling involved, we evaluated true lumen and false lumen diameters, and total aortic remodeling in CT. We analyzed 45 patients with Type B aortic dissection undergoing TEVAR. The mean ages were 66.9±10.0 years fo0072 IVUS (n = 20) and 62.3±14.2 years for CT-assisted TEVAR (n = 25; p = 0.226). The follow-up time for both groups did not differ between the two groups (IVUS: 22.9±23.1 months, CT: 25.6±23.0 months; p = 0.700). While both methods were associated with advantages regarding aortic remodeling, IVUS-assisted sizing yielded a greater increase in true lumen (30.4±6.2 vs. 25.6±5.3; p = 0.008) and reductions in false lumen (14.4±8.5 vs. 23.9±9.3; p = 0.001) and total aortic diameter (35.5±6.0 vs. 39.9±8.1; p = 0.045). IVUS-guided stent graft sizing in Type B aortic dissection shows beneficial effects on aortic remodeling and might be of additional advantage in aortic diseases, especially when CT image quality is poor. Public Library of Science 2018-04-19 /pmc/articles/PMC5908162/ /pubmed/29672613 http://dx.doi.org/10.1371/journal.pone.0196180 Text en © 2018 Lortz et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Lortz, Julia
Tsagakis, Konstantinos
Rammos, Christos
Horacek, Michael
Schlosser, Thomas
Jakob, Heinz
Rassaf, Tienush
Jánosi, Rolf Alexander
Intravascular ultrasound assisted sizing in thoracic endovascular aortic repair improves aortic remodeling in Type B aortic dissection
title Intravascular ultrasound assisted sizing in thoracic endovascular aortic repair improves aortic remodeling in Type B aortic dissection
title_full Intravascular ultrasound assisted sizing in thoracic endovascular aortic repair improves aortic remodeling in Type B aortic dissection
title_fullStr Intravascular ultrasound assisted sizing in thoracic endovascular aortic repair improves aortic remodeling in Type B aortic dissection
title_full_unstemmed Intravascular ultrasound assisted sizing in thoracic endovascular aortic repair improves aortic remodeling in Type B aortic dissection
title_short Intravascular ultrasound assisted sizing in thoracic endovascular aortic repair improves aortic remodeling in Type B aortic dissection
title_sort intravascular ultrasound assisted sizing in thoracic endovascular aortic repair improves aortic remodeling in type b aortic dissection
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908162/
https://www.ncbi.nlm.nih.gov/pubmed/29672613
http://dx.doi.org/10.1371/journal.pone.0196180
work_keys_str_mv AT lortzjulia intravascularultrasoundassistedsizinginthoracicendovascularaorticrepairimprovesaorticremodelingintypebaorticdissection
AT tsagakiskonstantinos intravascularultrasoundassistedsizinginthoracicendovascularaorticrepairimprovesaorticremodelingintypebaorticdissection
AT rammoschristos intravascularultrasoundassistedsizinginthoracicendovascularaorticrepairimprovesaorticremodelingintypebaorticdissection
AT horacekmichael intravascularultrasoundassistedsizinginthoracicendovascularaorticrepairimprovesaorticremodelingintypebaorticdissection
AT schlosserthomas intravascularultrasoundassistedsizinginthoracicendovascularaorticrepairimprovesaorticremodelingintypebaorticdissection
AT jakobheinz intravascularultrasoundassistedsizinginthoracicendovascularaorticrepairimprovesaorticremodelingintypebaorticdissection
AT rassaftienush intravascularultrasoundassistedsizinginthoracicendovascularaorticrepairimprovesaorticremodelingintypebaorticdissection
AT janosirolfalexander intravascularultrasoundassistedsizinginthoracicendovascularaorticrepairimprovesaorticremodelingintypebaorticdissection