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An ADAM-10 dependent EPCR shedding links meningococcal interaction with endothelial cells to purpura fulminans
Purpura fulminans is a deadly complication of Neisseria meningitidis infections due to extensive thrombosis of microvessels. Although a Disseminated Intra-vascular Coagulation syndrome (DIC) is frequently observed during Gram negative sepsis, it is rarely associated with extensive thrombosis like th...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908201/ https://www.ncbi.nlm.nih.gov/pubmed/29630665 http://dx.doi.org/10.1371/journal.ppat.1006981 |