Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling

Chronic neuropathic pain is a major morbidity of neural injury, yet its mechanisms are incompletely understood. Hypersensitivity to previously non-noxious stimuli (allodynia) is a common symptom. Here, we demonstrate that the onset of cold hypersensitivity precedes tactile allodynia in a model of pa...

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Detalles Bibliográficos
Autores principales: Cobos, Enrique J., Nickerson, Chelsea A., Gao, Fuying, Chandran, Vijayendran, Bravo-Caparrós, Inmaculada, González-Cano, Rafael, Riva, Priscilla, Andrews, Nick A., Latremoliere, Alban, Seehus, Corey R., Perazzoli, Gloria, Nieto, Francisco R., Joller, Nicole, Painter, Michio W., Ma, Chi Him Eddie, Omura, Takao, Chesler, Elissa J., Geschwind, Daniel H., Coppola, Giovanni, Rangachari, Manu, Woolf, Clifford J., Costigan, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908229/
https://www.ncbi.nlm.nih.gov/pubmed/29386116
http://dx.doi.org/10.1016/j.celrep.2018.01.006

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