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Nanoliposome C6-Ceramide Increases the Anti-tumor Immune Response and Slows Growth of Liver Tumors in Mice

BACKGROUND & AIMS: Ceramide, a sphingolipid metabolite, affects T-cell signaling, induces apoptosis of cancer cells, and slows tumor growth in mice. However, it has not been used as a chemotherapeutic agent because of its cell impermeability and precipitation in aqueous solution. We developed a...

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Detalles Bibliográficos
Autores principales:	Li, Guangfu, Liu, Dai, Kimchi, Eric T., Kaifi, Jussuf T., Qi, Xiaoqiang, Manjunath, Yariswamy, Liu, Xinjian, Deering, Tye, Avella, Diego M., Fox, Todd, Rockey, Don C., Schell, Todd D., Kester, Mark, Staveley-O’Carroll, Kevin F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908238/ https://www.ncbi.nlm.nih.gov/pubmed/29408569 http://dx.doi.org/10.1053/j.gastro.2017.10.050

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