Cargando…
Nonleukemic granulocytic sarcoma of orbit after blunt trauma: A case report and review of literature
RATIONALE: Granulocytic sarcoma without invasion of bone marrow or blood is very rare. The diagnosis of it is usually overlooked and the treatment has not reached a consensus. Meanwhile, the onset of this kind of disease is not clear. PATIENT CONCERNS: Diagnose patients in early stage and help choos...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908642/ https://www.ncbi.nlm.nih.gov/pubmed/29642189 http://dx.doi.org/10.1097/MD.0000000000010373 |
_version_ | 1783315751955857408 |
---|---|
author | Cheng, Yuan Yu, Chun’e Zhu, Sha Guo, Linghong Zhang, Yi Zhang, Yiwen Ma, Xuelei |
author_facet | Cheng, Yuan Yu, Chun’e Zhu, Sha Guo, Linghong Zhang, Yi Zhang, Yiwen Ma, Xuelei |
author_sort | Cheng, Yuan |
collection | PubMed |
description | RATIONALE: Granulocytic sarcoma without invasion of bone marrow or blood is very rare. The diagnosis of it is usually overlooked and the treatment has not reached a consensus. Meanwhile, the onset of this kind of disease is not clear. PATIENT CONCERNS: Diagnose patients in early stage and help choose the right treatment strategies. DIAGNOSES: The ultimate diagnosis was nonleukemic granulocytic sarcoma after blunt trauma. INTERVENTIONS: Surgery was the initial treatment option. Chemotherapy including idarubicin (70 mg, D1–D3) and cytosine arabinoside (100 mg, D1–D7) and radiotherapy of total 3,060 cGy were then administered but failed to control the disease. Hematopoietic stem cell transplantation was finally administered. OUTCOMES: No evidence of disease progression or spread according to the latest follow-up. LESSONS: The etiology of nonleukemic granulocytic still remains unclear, though trauma seems to be a potential predisposing factor and deserves more attention for early diagnosis and timely and proper treatment. Systemic chemotherapy is more effective than radiotherapy or surgery. Hematopoietic stem cell transplantation is an alternative choice after the failure of chemotherapy. |
format | Online Article Text |
id | pubmed-5908642 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Wolters Kluwer Health |
record_format | MEDLINE/PubMed |
spelling | pubmed-59086422018-04-30 Nonleukemic granulocytic sarcoma of orbit after blunt trauma: A case report and review of literature Cheng, Yuan Yu, Chun’e Zhu, Sha Guo, Linghong Zhang, Yi Zhang, Yiwen Ma, Xuelei Medicine (Baltimore) 4800 RATIONALE: Granulocytic sarcoma without invasion of bone marrow or blood is very rare. The diagnosis of it is usually overlooked and the treatment has not reached a consensus. Meanwhile, the onset of this kind of disease is not clear. PATIENT CONCERNS: Diagnose patients in early stage and help choose the right treatment strategies. DIAGNOSES: The ultimate diagnosis was nonleukemic granulocytic sarcoma after blunt trauma. INTERVENTIONS: Surgery was the initial treatment option. Chemotherapy including idarubicin (70 mg, D1–D3) and cytosine arabinoside (100 mg, D1–D7) and radiotherapy of total 3,060 cGy were then administered but failed to control the disease. Hematopoietic stem cell transplantation was finally administered. OUTCOMES: No evidence of disease progression or spread according to the latest follow-up. LESSONS: The etiology of nonleukemic granulocytic still remains unclear, though trauma seems to be a potential predisposing factor and deserves more attention for early diagnosis and timely and proper treatment. Systemic chemotherapy is more effective than radiotherapy or surgery. Hematopoietic stem cell transplantation is an alternative choice after the failure of chemotherapy. Wolters Kluwer Health 2018-04-13 /pmc/articles/PMC5908642/ /pubmed/29642189 http://dx.doi.org/10.1097/MD.0000000000010373 Text en Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 |
spellingShingle | 4800 Cheng, Yuan Yu, Chun’e Zhu, Sha Guo, Linghong Zhang, Yi Zhang, Yiwen Ma, Xuelei Nonleukemic granulocytic sarcoma of orbit after blunt trauma: A case report and review of literature |
title | Nonleukemic granulocytic sarcoma of orbit after blunt trauma: A case report and review of literature |
title_full | Nonleukemic granulocytic sarcoma of orbit after blunt trauma: A case report and review of literature |
title_fullStr | Nonleukemic granulocytic sarcoma of orbit after blunt trauma: A case report and review of literature |
title_full_unstemmed | Nonleukemic granulocytic sarcoma of orbit after blunt trauma: A case report and review of literature |
title_short | Nonleukemic granulocytic sarcoma of orbit after blunt trauma: A case report and review of literature |
title_sort | nonleukemic granulocytic sarcoma of orbit after blunt trauma: a case report and review of literature |
topic | 4800 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908642/ https://www.ncbi.nlm.nih.gov/pubmed/29642189 http://dx.doi.org/10.1097/MD.0000000000010373 |
work_keys_str_mv | AT chengyuan nonleukemicgranulocyticsarcomaoforbitafterblunttraumaacasereportandreviewofliterature AT yuchune nonleukemicgranulocyticsarcomaoforbitafterblunttraumaacasereportandreviewofliterature AT zhusha nonleukemicgranulocyticsarcomaoforbitafterblunttraumaacasereportandreviewofliterature AT guolinghong nonleukemicgranulocyticsarcomaoforbitafterblunttraumaacasereportandreviewofliterature AT zhangyi nonleukemicgranulocyticsarcomaoforbitafterblunttraumaacasereportandreviewofliterature AT zhangyiwen nonleukemicgranulocyticsarcomaoforbitafterblunttraumaacasereportandreviewofliterature AT maxuelei nonleukemicgranulocyticsarcomaoforbitafterblunttraumaacasereportandreviewofliterature |