Adult-onset Minimal Change Disease with IgA Nephropathy and Hepatitis C

Minimal change disease (MCD) is one of the most common causes of nephrotic syndrome in children, leading to heavy proteinuria and edema. However, it is not as common in adults. Adult-onset minimal change disease with IgA nephropathy is rare. The initial presentation of heavy proteinuria and edema wi...

Descripción completa

Detalles Bibliográficos
Autores principales: Chowdhury, Waliul, Saleem, Tahira Sabeen, Lodhi, Muhammad Uzair, Syed, Intekhab Askari, Iqbal, Hafiz Imran, Rahim, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Family/General Practice
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908716/
https://www.ncbi.nlm.nih.gov/pubmed/29682437
http://dx.doi.org/10.7759/cureus.2207
_version_ 1783315756725829632
author Chowdhury, Waliul
Saleem, Tahira Sabeen
Lodhi, Muhammad Uzair
Syed, Intekhab Askari
Iqbal, Hafiz Imran
Rahim, Mustafa
author_facet Chowdhury, Waliul
Saleem, Tahira Sabeen
Lodhi, Muhammad Uzair
Syed, Intekhab Askari
Iqbal, Hafiz Imran
Rahim, Mustafa
author_sort Chowdhury, Waliul
collection PubMed
description Minimal change disease (MCD) is one of the most common causes of nephrotic syndrome in children, leading to heavy proteinuria and edema. However, it is not as common in adults. Adult-onset minimal change disease with IgA nephropathy is rare. The initial presentation of heavy proteinuria and edema with effacement of podocytes on electron microscopy (EM) should lead the physician to suspect minimal change disease regardless of age. We present a 44-year-old male patient with a history of hepatitis C virus (HCV) who presented with sudden onset of lower extremity edema and 6.6 grams (g) of proteinuria per day.
format Online
Article
Text
id pubmed-5908716
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-59087162018-04-20 Adult-onset Minimal Change Disease with IgA Nephropathy and Hepatitis C Chowdhury, Waliul Saleem, Tahira Sabeen Lodhi, Muhammad Uzair Syed, Intekhab Askari Iqbal, Hafiz Imran Rahim, Mustafa Cureus Family/General Practice Minimal change disease (MCD) is one of the most common causes of nephrotic syndrome in children, leading to heavy proteinuria and edema. However, it is not as common in adults. Adult-onset minimal change disease with IgA nephropathy is rare. The initial presentation of heavy proteinuria and edema with effacement of podocytes on electron microscopy (EM) should lead the physician to suspect minimal change disease regardless of age. We present a 44-year-old male patient with a history of hepatitis C virus (HCV) who presented with sudden onset of lower extremity edema and 6.6 grams (g) of proteinuria per day. Cureus 2018-02-19 /pmc/articles/PMC5908716/ /pubmed/29682437 http://dx.doi.org/10.7759/cureus.2207 Text en Copyright © 2018, Chowdhury et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Family/General Practice
Chowdhury, Waliul
Saleem, Tahira Sabeen
Lodhi, Muhammad Uzair
Syed, Intekhab Askari
Iqbal, Hafiz Imran
Rahim, Mustafa
Adult-onset Minimal Change Disease with IgA Nephropathy and Hepatitis C
title Adult-onset Minimal Change Disease with IgA Nephropathy and Hepatitis C
title_full Adult-onset Minimal Change Disease with IgA Nephropathy and Hepatitis C
title_fullStr Adult-onset Minimal Change Disease with IgA Nephropathy and Hepatitis C
title_full_unstemmed Adult-onset Minimal Change Disease with IgA Nephropathy and Hepatitis C
title_short Adult-onset Minimal Change Disease with IgA Nephropathy and Hepatitis C
title_sort adult-onset minimal change disease with iga nephropathy and hepatitis c
topic Family/General Practice
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908716/
https://www.ncbi.nlm.nih.gov/pubmed/29682437
http://dx.doi.org/10.7759/cureus.2207
work_keys_str_mv AT chowdhurywaliul adultonsetminimalchangediseasewithiganephropathyandhepatitisc
AT saleemtahirasabeen adultonsetminimalchangediseasewithiganephropathyandhepatitisc
AT lodhimuhammaduzair adultonsetminimalchangediseasewithiganephropathyandhepatitisc
AT syedintekhabaskari adultonsetminimalchangediseasewithiganephropathyandhepatitisc
AT iqbalhafizimran adultonsetminimalchangediseasewithiganephropathyandhepatitisc
AT rahimmustafa adultonsetminimalchangediseasewithiganephropathyandhepatitisc

Ejemplares similares