Cargando…

Association of STAT-3 rs1053004 and VDR rs11574077 With FOLFIRI-Related Gastrointestinal Toxicity in Metastatic Colorectal Cancer Patients

Pharmacogenomics has largely been applied to the personalization of irinotecan-based treatment, focusing mainly on the study of genetic variants in adsorption, distribution, metabolism, and excretion (ADME) genes. The transcriptional control of ADME gene expression is mediated by a set of nuclear fa...

Descripción completa

Detalles Bibliográficos
Autores principales: De Mattia, Elena, Cecchin, Erika, Montico, Marcella, Labriet, Adrien, Guillemette, Chantal, Dreussi, Eva, Roncato, Rossana, Bignucolo, Alessia, Buonadonna, Angela, D’Andrea, Mario, Coppola, Luigi, Lonardi, Sara, Lévesque, Eric, Jonker, Derek, Couture, Félix, Toffoli, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908896/
https://www.ncbi.nlm.nih.gov/pubmed/29706892
http://dx.doi.org/10.3389/fphar.2018.00367