Cargando…

A Serum Circulating miRNA Signature for Short-Term Risk of Progression to Active Tuberculosis Among Household Contacts

Biomarkers that predict who among recently Mycobacterium tuberculosis (MTB)-exposed individuals will progress to active tuberculosis are urgently needed. Intracellular microRNAs (miRNAs) regulate the host response to MTB and circulating miRNAs (c-miRNAs) have been developed as biomarkers for other d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Duffy, Fergal J., Thompson, Ethan, Downing, Katrina, Suliman, Sara, Mayanja-Kizza, Harriet, Boom, W. Henry, Thiel, Bonnie, Weiner III, January, Kaufmann, Stefan H. E., Dover, Drew, Tabb, David L., Dockrell, Hazel M., Ottenhoff, Tom H. M., Tromp, Gerard, Scriba, Thomas J., Zak, Daniel E., Walzl, Gerhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5908968/ https://www.ncbi.nlm.nih.gov/pubmed/29706954 http://dx.doi.org/10.3389/fimmu.2018.00661

Ejemplares similares

Metabolite changes in blood predict the onset of tuberculosis
por: Weiner, January, et al.
Publicado: (2018)

Immunometabolic Signatures Predict Risk of Progression to Active Tuberculosis and Disease Outcome
por: Duffy, Fergal J., et al.
Publicado: (2019)

A prospective blood RNA signature for tuberculosis disease risk
por: Zak, Daniel E., et al.
Publicado: (2016)

Neutrophil degranulation, NETosis and platelet degranulation pathway genes are co-induced in whole blood up to six months before tuberculosis diagnosis
por: Meier, Stuart, et al.
Publicado: (2022)

Multinomial modelling of TB/HIV co-infection yields a robust predictive signature and generates hypotheses about the HIV+TB+ disease state
por: Duffy, Fergal J., et al.
Publicado: (2019)

Concise gene signature for point‐of‐care classification of tuberculosis
por: Maertzdorf, Jeroen, et al.
Publicado: (2015)

Analysis of Host Responses to Mycobacterium tuberculosis Antigens in a Multi-Site Study of Subjects with Different TB and HIV Infection States in Sub-Saharan Africa
por: Sutherland, Jayne S., et al.
Publicado: (2013)

Suitability of saliva for Tuberculosis diagnosis: comparing with serum
por: Namuganga, Anna Ritah, et al.
Publicado: (2017)

Diagnostic Accuracy of the Cepheid 3-gene Host Response Fingerstick Blood Test in a Prospective, Multi-site Study: Interim Results
por: Sutherland, Jayne S, et al.
Publicado: (2021)

Tuberculin Skin Test Reversion following Isoniazid Preventive Therapy Reflects Diversity of Immune Response to Primary Mycobacterium tuberculosis Infection
por: Johnson, Denise F., et al.
Publicado: (2014)

The Peripheral Blood Transcriptome Is Correlated With PET Measures of Lung Inflammation During Successful Tuberculosis Treatment
por: Odia, Trust, et al.
Publicado: (2021)

Patient and health service delay in pulmonary tuberculosis patients attending a referral hospital: a cross-sectional study
por: Kiwuwa, Mpungu S, et al.
Publicado: (2005)

Host blood RNA signatures predict the outcome of tuberculosis treatment
por: Thompson, Ethan G., et al.
Publicado: (2017)

The effect of interrupted anti-retroviral treatment on the reconstitution of memory and naive T cells during tuberculosis treatment in HIV patients with active pulmonary tuberculosis
por: Nalukwago, Sophie, et al.
Publicado: (2017)

Clinical and epidemiological characteristics of individuals resistant to M. tuberculosis infection in a longitudinal TB household contact study in Kampala, Uganda
por: Ma, Ningning, et al.
Publicado: (2014)

Mind the gaps: a qualitative study of perceptions of healthcare professionals on challenges and proposed remedies for cervical cancer help-seeking in post conflict northern Uganda
por: Mwaka, Amos D, et al.
Publicado: (2013)

Experiences of patients who developed oral mucositis during solid neoplasms treatment: a Ugandan qualitative study
por: Kamulegeya, Adriane, et al.
Publicado: (2021)

Past and Present Approaches to Diagnosis of Active Pulmonary Tuberculosis
por: Namuganga, Anna Ritah, et al.
Publicado: (2021)

Editorial: Immuno-diagnosis of active tuberculosis; are we making progress?
por: Mayanja-Kizza, Harriet, et al.
Publicado: (2023)

Differential transcriptomic and metabolic profiles of M. africanum- and M. tuberculosis-infected patients after, but not before drug treatment
por: Tientcheu, Leopold D., et al.
Publicado: (2015)

Validation and Optimization of Host Immunological Bio-Signatures for a Point-of-Care Test for TB Disease
por: Mutavhatsindi, Hygon, et al.
Publicado: (2021)

Whole Blood Interferon-Gamma Responses to Mycobacterium tuberculosis Antigens in Young Household Contacts of Persons with Tuberculosis in Uganda
por: Lewinsohn, Deborah A., et al.
Publicado: (2008)

Digital clubbing in tuberculosis – relationship to HIV infection, extent of disease and hypoalbuminemia
por: Ddungu, Henry, et al.
Publicado: (2006)

Extensive dental caries in a HIV positive adult patient on ART; case report and literature review
por: Kalanzi, Dunstan, et al.
Publicado: (2018)

Detection of Tuberculosis Recurrence, Diagnosis and Treatment Response by a Blood Transcriptomic Risk Signature in HIV-Infected Persons on Antiretroviral Therapy
por: Darboe, Fatoumatta, et al.
Publicado: (2019)

Vitamin D deficiency among adult patients with tuberculosis: a cross sectional study from a national referral hospital in Uganda
por: Kibirige, Davis, et al.
Publicado: (2013)

The Clinical Presentation and Factors Associated with Disease Severity of Rheumatoid Arthritis in Uganda: A Cross-Sectional Study
por: Ochola, Ben, et al.
Publicado: (2022)

Immune cells in bronchoalveolar lavage fluid of Ugandan adults who resist versus those who develop latent Mycobacterium tuberculosis infection
por: Thiel, Bonnie A., et al.
Publicado: (2021)

Resistance to TST/IGRA conversion in Uganda: Heritability and Genome-Wide Association Study
por: McHenry, Michael L, et al.
Publicado: (2021)

Differentially expressed transcript isoforms associate with resistance to tuberculin skin test and interferon gamma release assay conversion
por: Simmons, Jason D., et al.
Publicado: (2023)

Sero-prevalence and risk factors for hepatitis B virus infection among health care workers in a tertiary hospital in Uganda
por: Ziraba, Abdhalah K, et al.
Publicado: (2010)

The Effect of a Bidirectional Exchange on Faculty and Institutional Development in a Global Health Collaboration
por: Bodnar, Benjamin E., et al.
Publicado: (2015)

Differential DNA methylation of potassium channel KCa3.1 and immune signalling pathways is associated with infant immune responses following BCG vaccination
por: Hasso-Agopsowicz, Mateusz, et al.
Publicado: (2018)

Mycobacterium tuberculosis-dependent Monocyte Expression Quantitative Trait Loci and Tuberculosis Pathogenesis
por: Hong, Hyejeong, et al.
Publicado: (2023)

Immune Activation at Sites of HIV/TB Co-Infection Contributes to the Pathogenesis of HIV-1 Disease
por: Meng, Qinglai, et al.
Publicado: (2016)

Prevalence and factors associated with dental caries in patients attending an HIV care clinic in Uganda: a cross sectional study
por: Kalanzi, Dunstan, et al.
Publicado: (2019)

Genetic variability and consequence of Mycobacterium tuberculosis lineage 3 in Kampala-Uganda
por: Wampande, Eddie M., et al.
Publicado: (2019)

Interaction between M. tuberculosis Lineage and Human Genetic Variants Reveals Novel Pathway Associations with Severity of TB
por: McHenry, Michael L., et al.
Publicado: (2021)

336. Developing a Protein Signature of Early Latent Tuberculosis Infection.
por: Bark, Charles, et al.
Publicado: (2022)

Considerations for biomarker-targeted intervention strategies for tuberculosis disease prevention
por: Fiore-Gartland, Andrew, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_d8vhuheiudi1sfhn5j5ausnfu1