Pituitary fossa chondrosarcoma: An unusual cause of a sellar suprasellar mass masquerading as pituitary adenoma

BACKGROUND: Chondrosarcoma is a mesenchymal malignant tumor composed of tumor cells producing cartilage. It is more commonly found in older age group and usually affects the axial skeleton. Intracranial chondrosarcoma is extremely rare, and chondrosarcoma arising from the sellar region are even rarer with only a few cases described in the literature. We report a case of chondrosarcoma mimicking a sellar suprasellar mass with parasellar extension. CASE DESCRIPTION: A 22-year old male presented with generalized intermittent headache along with diplopia and diminished visual acuity without any history of sexual dysfunction or galactorrhea. His endocrine tests were within normal limits. Magnetic resonance imaging of the brain revealed a large mass which was apparently arising from the sella with a significant suprasellar and left parasellar component with mild compression over the left optic chiasm and deviation of infundibulum to the right. The patient underwent pterional craniotomy and decompression of the mass. The pathologic diagnosis was chondrosarcoma. The patient received postoperative radiotherapy. CONCLUSION: This case demonstrates that chondrosarcoma of the sellar region may mimic clinical, endocrinological, and radiological features of more commonly encountered lesions in this region such as nonfunctioning pituitary tumor, craniopharyngioma, meningioma, or chordoma. We discuss the origin, areas of involvement, management, and long-term prognosis of these rare tumors.