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Long noncoding RNA H19 upregulates vascular endothelial growth factor A to enhance mesenchymal stem cells survival and angiogenic capacity by inhibiting miR-199a-5p
BACKGROUND: Currently, the overall therapeutic efficiency of mesenchymal stem cells (MSCs) transplantation for the treatment of cardiovascular disease is not satisfactory. The low viability and angiogenic capacity of the implanted cells in the local infarct tissues restrict their further application...
Autores principales: | Hou, Jingying, Wang, Lingyun, Wu, Quanhua, Zheng, Guanghui, Long, Huibao, Wu, Hao, Zhou, Changqing, Guo, Tianzhu, Zhong, Tingting, Wang, Lei, Chen, Xuxiang, Wang, Tong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909270/ https://www.ncbi.nlm.nih.gov/pubmed/29673400 http://dx.doi.org/10.1186/s13287-018-0861-x |
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