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Maturation of the 90S pre-ribosome requires Mrd1 dependent U3 snoRNA and 35S pre-rRNA structural rearrangements

In eukaryotes, ribosome biogenesis requires folding and assembly of the precursor rRNA (pre-rRNA) with a large number of proteins and snoRNPs into huge RNA-protein complexes. In spite of intense genetic, biochemical and high-resolution cryo-EM studies in Saccharomyces cerevisiae, information about t...

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Detalles Bibliográficos
Autores principales:	Lackmann, Fredrik, Belikov, Sergey, Burlacu, Elena, Granneman, Sander, Wieslander, Lars
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	RNA Prot Comp
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909432/ https://www.ncbi.nlm.nih.gov/pubmed/29373706 http://dx.doi.org/10.1093/nar/gky036

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