Diff-seq: A high throughput sequencing-based mismatch detection assay for DNA variant enrichment and discovery

Much of the within species genetic variation is in the form of single nucleotide polymorphisms (SNPs), typically detected by whole genome sequencing (WGS) or microarray-based technologies. However, WGS produces mostly uninformative reads that perfectly match the reference, while microarrays require...

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Detalles Bibliográficos
Autores principales: Aggeli, Dimitra, Karas, Vlad O, Sinnott-Armstrong, Nicholas A, Varghese, Vici, Shafer, Robert W, Greenleaf, William J, Sherlock, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909455/
https://www.ncbi.nlm.nih.gov/pubmed/29361139
http://dx.doi.org/10.1093/nar/gky022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909455/
https://www.ncbi.nlm.nih.gov/pubmed/29361139
http://dx.doi.org/10.1093/nar/gky022

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