Kill two birds with one stone: making multi-transgenic pre-diabetes mouse models through insulin resistance and pancreatic apoptosis pathogenesis

BACKGROUND: Type 2 diabetes is characterized by insulin resistance accompanied by defective insulin secretion. Transgenic mouse models play an important role in medical research. However, single transgenic mouse models may not mimic the complex phenotypes of most cases of type 2 diabetes. METHODS: F...

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Detalles Bibliográficos
Autores principales: Kong, Siyuan, Ruan, Jinxue, Zhang, Kaiyi, Hu, Bingjun, Cheng, Yuzhu, Zhang, Yubo, Yang, Shulin, Li, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Agricultural Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909684/
https://www.ncbi.nlm.nih.gov/pubmed/29682407
http://dx.doi.org/10.7717/peerj.4542

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