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Recanalization and remodeling of the great saphenous vein caused by the large melanoma’s cutaneous metastasis

AIM OF THE STUDY: Large melanoma tumour caused arterial remodelling of the distal part of the great saphenous vein. The metastasis occurred at the site where inguinal lymphadenectomy was previously performed and the proximal part of the great saphenous vein was resected. The aim of this study is the...

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Autores principales: Stefaniak, Przemysław, Kwiatkowski, Przemysław, Kozielec, Zygmunt, Godlewski, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909732/
https://www.ncbi.nlm.nih.gov/pubmed/29692666
http://dx.doi.org/10.5114/wo.2018.74396
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author Stefaniak, Przemysław
Kwiatkowski, Przemysław
Kozielec, Zygmunt
Godlewski, Janusz
author_facet Stefaniak, Przemysław
Kwiatkowski, Przemysław
Kozielec, Zygmunt
Godlewski, Janusz
author_sort Stefaniak, Przemysław
collection PubMed
description AIM OF THE STUDY: Large melanoma tumour caused arterial remodelling of the distal part of the great saphenous vein. The metastasis occurred at the site where inguinal lymphadenectomy was previously performed and the proximal part of the great saphenous vein was resected. The aim of this study is the presentation of such a rare observation and literature overview concerning melanoma metastasis and possible stimuli causing remodelling of veins. MATERIAL AND METHODS: Macroscopic and microscopic analyses of the large blood vessel that supplies melanoma were made. The size and structure of the blood vessel was compared with the regular great saphenous vein. RESULTS: The macroscopic examinations allowed us to ascertain that the blood vessel that was identified intraoperatively as the great saphenous vein, has a thick, stiff wall. The microscopic analysis allowed demonstrated that the tunica media was typical for a muscular artery morphology. The morphometric analysis revealed that the blood vessel wall in the area of metastatic tumour was much thicker than the wall of a regular great saphenous vein. CONCLUSIONS: This malignant melanoma skin metastases caused the recanalisation of the great saphenous vein the lumen of which was obliterated during the initial surgical treatment. The metastatic tumour supplied by large blood vessels grew extensively and caused arterial remodelling of the venous wall.
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spelling pubmed-59097322018-04-24 Recanalization and remodeling of the great saphenous vein caused by the large melanoma’s cutaneous metastasis Stefaniak, Przemysław Kwiatkowski, Przemysław Kozielec, Zygmunt Godlewski, Janusz Contemp Oncol (Pozn) Case Report AIM OF THE STUDY: Large melanoma tumour caused arterial remodelling of the distal part of the great saphenous vein. The metastasis occurred at the site where inguinal lymphadenectomy was previously performed and the proximal part of the great saphenous vein was resected. The aim of this study is the presentation of such a rare observation and literature overview concerning melanoma metastasis and possible stimuli causing remodelling of veins. MATERIAL AND METHODS: Macroscopic and microscopic analyses of the large blood vessel that supplies melanoma were made. The size and structure of the blood vessel was compared with the regular great saphenous vein. RESULTS: The macroscopic examinations allowed us to ascertain that the blood vessel that was identified intraoperatively as the great saphenous vein, has a thick, stiff wall. The microscopic analysis allowed demonstrated that the tunica media was typical for a muscular artery morphology. The morphometric analysis revealed that the blood vessel wall in the area of metastatic tumour was much thicker than the wall of a regular great saphenous vein. CONCLUSIONS: This malignant melanoma skin metastases caused the recanalisation of the great saphenous vein the lumen of which was obliterated during the initial surgical treatment. The metastatic tumour supplied by large blood vessels grew extensively and caused arterial remodelling of the venous wall. Termedia Publishing House 2018-04-03 2018 /pmc/articles/PMC5909732/ /pubmed/29692666 http://dx.doi.org/10.5114/wo.2018.74396 Text en Copyright: © 2018 Termedia Sp. z o. o. http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Case Report
Stefaniak, Przemysław
Kwiatkowski, Przemysław
Kozielec, Zygmunt
Godlewski, Janusz
Recanalization and remodeling of the great saphenous vein caused by the large melanoma’s cutaneous metastasis
title Recanalization and remodeling of the great saphenous vein caused by the large melanoma’s cutaneous metastasis
title_full Recanalization and remodeling of the great saphenous vein caused by the large melanoma’s cutaneous metastasis
title_fullStr Recanalization and remodeling of the great saphenous vein caused by the large melanoma’s cutaneous metastasis
title_full_unstemmed Recanalization and remodeling of the great saphenous vein caused by the large melanoma’s cutaneous metastasis
title_short Recanalization and remodeling of the great saphenous vein caused by the large melanoma’s cutaneous metastasis
title_sort recanalization and remodeling of the great saphenous vein caused by the large melanoma’s cutaneous metastasis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909732/
https://www.ncbi.nlm.nih.gov/pubmed/29692666
http://dx.doi.org/10.5114/wo.2018.74396
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