Cargando…

Targeted Drug Delivery in the Suprachoroidal Space by Swollen Hydrogel Pushing

PURPOSE: The purpose is to target model drug particles to the posterior region of the suprachoroidal space (SCS) of the eye controlled via pushing by hydrogel swelling. METHODS: A particle formulation containing 1% hyaluronic acid (HA) with fluorescent polymer particles and a hydrogel formulation co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jung, Jae Hwan, Desit, Patcharin, Prausnitz, Mark R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2018
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909801/ https://www.ncbi.nlm.nih.gov/pubmed/29677369 http://dx.doi.org/10.1167/iovs.17-23758

Ejemplares similares

Suprachoroidal Delivery in Rats and Guinea Pigs Using a High-Precision Microneedle Injector
por: Hejri, Amir, et al.
Publicado: (2023)

A Novel Device for Suprachoroidal Drug Delivery to Retina: Evaluation in Nonhuman Primates
por: Rotenstreich, Ygal, et al.
Publicado: (2023)

Three-Dimensional Transport Model for Intravitreal and Suprachoroidal Drug Injection
por: Zhang, Yu, et al.
Publicado: (2018)

Estimating Phosphene Locations Using Eye Movements of Suprachoroidal Retinal Prosthesis Users
por: Titchener, Samuel A., et al.
Publicado: (2023)

Interobserver Agreement of Electrode to Retina Distance Measurements in a Second-Generation (44-Channel) Suprachoroidal Retinal Prosthesis
por: Abbott, Carla J., et al.
Publicado: (2022)

Thickness and Closure Kinetics of the Suprachoroidal Space Following Microneedle Injection of Liquid Formulations
por: Chiang, Bryce, et al.
Publicado: (2017)

Drug‐Free, Nonsurgical Reduction of Intraocular Pressure for Four Months after Suprachoroidal Injection of Hyaluronic Acid Hydrogel
por: Chae, J. Jeremy, et al.
Publicado: (2020)

Drug Delivery via the Suprachoroidal Space for the Treatment of Retinal Diseases
por: Naftali Ben Haim, Liron, et al.
Publicado: (2021)

Clearance Kinetics and Clearance Routes of Molecules From the Suprachoroidal Space After Microneedle Injection
por: Chiang, Bryce, et al.
Publicado: (2017)

Modified posterior drainage of post-operative suprachoroidal hemorrhage
por: Boral, Subhendu Kumar, et al.
Publicado: (2021)

Extended Intravitreal Rabbit Eye Residence of Nanoparticles Conjugated With Cationic Arginine Peptides for Intraocular Drug Delivery: In Vivo Imaging
por: Melgar-Asensio, Ignacio, et al.
Publicado: (2018)

Improvement of Photoreceptor Targeting via Intravitreal Delivery in Mouse and Human Retina Using Combinatory rAAV2 Capsid Mutant Vectors
por: Reid, Christopher A., et al.
Publicado: (2017)

Suprachoroidal Injection: A Novel Approach for Targeted Drug Delivery
por: Wu, Kevin Y., et al.
Publicado: (2023)

A Pharmacodynamic Analysis of Choroidal Neovascularization in a Porcine Model Using Three Targeted Drugs
por: Tran, Jeffrey, et al.
Publicado: (2017)

Cone Spacing Correlates With Retinal Thickness and Microperimetry in Patients With Inherited Retinal Degenerations
por: Foote, Katharina G., et al.
Publicado: (2019)

Clinical Relevance of Parafoveal Intercapillary Spaces and Foveal Avascular Zone in Diabetic Retinopathy Without Macular Edema
por: Terada, Noriko, et al.
Publicado: (2022)

Allogeneic iPSC-Derived RPE Cell Graft Failure Following Transplantation Into the Subretinal Space in Nonhuman Primates
por: McGill, Trevor J., et al.
Publicado: (2018)

Controlled Release of Dexamethasone From an Intravitreal Delivery System Using Porous Silicon Dioxide
por: Hou, Huiyuan, et al.
Publicado: (2016)

Sustained Ocular Delivery of Bevacizumab Using Densomeres in Rabbits: Effects on Molecular Integrity and Bioactivity
por: Peterson, Jan S., et al.
Publicado: (2023)

Inner Retinal Oxygen Delivery, Metabolism, and Extraction Fraction in Ins2(Akita) Diabetic Mice
por: Blair, Norman P., et al.
Publicado: (2016)

Retinal Oxygen Delivery and Metabolism Response to Hyperoxia During Bilateral Common Carotid Artery Occlusion in Rats
por: Leahy, Sophie, et al.
Publicado: (2022)

Alterations in Retinal Oxygen Delivery, Metabolism, and Extraction Fraction During Bilateral Common Carotid Artery Occlusion in Rats
por: Karamian, Preny, et al.
Publicado: (2019)

A Long-Term Safety and Efficacy Report on Intravitreal Delivery of Adipose Stem Cells and Secretome on Visual Deficits After Traumatic Brain Injury
por: Rasiah, Pratheepa Kumari, et al.
Publicado: (2022)

Targeted Blood Metabolomic Study on Retinopathy of Prematurity
por: Yang, Yuhang, et al.
Publicado: (2020)

Subretinal Rather Than Intravitreal Adeno-Associated Virus–Mediated Delivery of a Complement Alternative Pathway Inhibitor Is Effective in a Mouse Model of RPE Damage
por: Annamalai, Balasubramaniam, et al.
Publicado: (2021)

The suprachoroidal space: from potential space to a space with potential
por: Moisseiev, Elad, et al.
Publicado: (2016)

Local Myeloid-Derived Suppressor Cells Impair Progression of Experimental Autoimmune Uveitis by Alleviating Oxidative Stress and Inflammation
por: Lee, Jae-Young, et al.
Publicado: (2023)

Impacts of Systemic Hypertension on the Macular Microvasculature in Diabetic Patients Without Clinical Diabetic Retinopathy
por: Lee, Min-Woo, et al.
Publicado: (2021)

The Ganglion Cell-Inner Plexiform Layer Thickness/Vessel Density of Superficial Vascular Plexus Ratio According to the Progression of Diabetic Retinopathy
por: Sung, Jae-Yun, et al.
Publicado: (2022)

Preclinical Efficacy and Safety of VEGF-Grab, a Novel Anti-VEGF Drug, and Its Comparison to Aflibercept
por: Hong, Hye Kyoung, et al.
Publicado: (2020)

Xanthatin Selectively Targets Retinoblastoma by Inhibiting the PLK1-Mediated Cell Cycle
por: Yang, Jie, et al.
Publicado: (2021)

Probable Treatment Targets for Diabetic Retinopathy Based on an Integrated Proteomic and Genomic Analysis
por: Valdivia, Anddre Osmar, et al.
Publicado: (2023)

Identification of Novel Retinal Pericyte-Targeting rAAV Vectors Through Directed Evolution
por: Patel, Dwani D., et al.
Publicado: (2022)

Targeted Analysis of Tears Revealed Specific Altered Metal Homeostasis in Age-Related Macular Degeneration
por: Valencia, Eva, et al.
Publicado: (2022)

Suppression of Pathological Ocular Neovascularization by a Small Molecular Multi-Targeting Kinase Inhibitor, DCZ19903
por: Ding, Jingjuan, et al.
Publicado: (2022)

A Study of the Association Between Retinal Vessel Geometry and Optical Coherence Tomography Angiography Metrics in Diabetic Retinopathy
por: Choi, Ji Min, et al.
Publicado: (2021)

Immunosubunit β5i Knockout Suppresses Neovascularization and Restores Autophagy in Retinal Neovascularization by Targeting ATG5 for Degradation
por: Ji, Liyang, et al.
Publicado: (2020)

MicroRNA-92a-3p Regulates Retinal Angiogenesis by Targeting SGK3 in Vascular Endothelial Cells
por: Cui, Yamei, et al.
Publicado: (2022)

Blast Preconditioning Protects Retinal Ganglion Cells and Reveals Targets for Prevention of Neurodegeneration Following Blast-Mediated Traumatic Brian Injury
por: Harper, Matthew M., et al.
Publicado: (2019)

Targeting Plasma Kallikrein With a Novel Bicyclic Peptide Inhibitor (THR-149) Reduces Retinal Thickening in a Diabetic Rat Model
por: Van Bergen, Tine, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qkf44r135telsl9gp1pdq90kgf